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02-22-2014, 10:15 AM | #71 | ||
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Mine has rs1801133 AG +- which means I have one mutation and one normal (heterzygous). Minus is good. You should show two though.
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"Thanks for this!" says: | anagirl (02-22-2014) |
03-25-2014, 07:33 AM | #72 | |||
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Quote:
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John Diag. Mar 2008 YOPD, @ age 39 |
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03-25-2014, 04:31 PM | #73 | ||
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I just completed one bottle of the MCT oil and I haven't really noticed a difference. I have had 2 bad colds during this time, so maybe I"m not feeling better because my system is off. Or maybe because it just doesn't make a difference...?
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"Thanks for this!" says: | Drevy (03-26-2014) |
03-29-2014, 08:44 AM | #74 | ||
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Wow...about 8 tablespoons...that's 1/2 a cup. Are you really suppose to take this much per day?
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04-15-2014, 08:17 PM | #75 | ||
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I have been using coconut oil for over a year now and can share some of my experiences:
(1) I am taking what many would consider massive doses, up to 12 TBS per day. My blood work has changed dramatically for the better in all respects (except for fasting glucose, which remained a little on the high side 140, more about that latter) (2) MCT oil is indeed more ketogenic than coconut oil. In fact C-8 MCT oil is the most ketogenic of them all. Coconut oil however has a lot more going for it than just ketones so I recommend trying a 50-50 mixture. (3) Serum ketone levels are depressed with the ingestion of carbohydrate. People with a tendency towards insulin resistance have a greater insulin reaction to carbohydrate. Practicing a low carb diet will result in a ten fold increase in serum ketones 1 - 3 mM/l, compared to taking coconut oil with a conventional balanced meal with carbohydrate (The Art and Science of Low Carbohydrate Living by Phinney & Volek). You must also restrict protein, usually to under 120 g per day, but you must be careful with this. Fasting glucose is now 80-100. (3) The higher the serum ketones level, the better I feel and the PD symptoms fade away. Ketone levels are self regulating on a ketogenic diet. Scientific feasibility studies of a hyperketogenic diet (90 % fat) can elevate serum ketone to 4 - 8 mM/l (4) I take a combination of coconut oil, C-8 MCT oil and ketone salts to help moderate my serum ketone levels throughout the day. I take a blood sample each morning before breakfast, as a basis for starting my ketone supplementation for the day. Supplementation for the rest of the day is based on my symptoms. |
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04-15-2014, 11:47 PM | #76 | ||
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Satwar,
Thank you for a very informative post. With a daily blood test, you have taken self analysis to new levels. Do you collect any objective symptom data, such as side to side tap test or time to walk a mile etc.? John
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Born 1955. Diagnosed PD 2005. Meds 2010-Nov 2016: Stalevo(75 mg) x 4, ropinirole xl 16 mg, rasagiline 1 mg Current meds: Stalevo(75 mg) x 5, ropinirole xl 8 mg, rasagiline 1 mg |
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04-16-2014, 06:34 AM | #77 | ||
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04-16-2014, 06:45 AM | #78 | ||
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No I don't do any symptom testing as my primary symptom is a strong tremor and it is very clear when it leaves. My Mirapex has a slight reduction of tremor, but nothing compared to ketones. I should qualify that stress brings the tremor back out, even @ 3 mM/l, but it can be more easily brought back under control, which I can't do without ketones. I have been up to 5.5 mM/l and find that there is a continuum of improvement in symptoms.
I am trying to focus on learning how to achieve higher serum ketones. I have not experimented with reducing medication. I'm concerned with sustaining a reliable ketone level, and an improved quality of life. Living low carbohydrate with ketone supplementation has significantly improved my quality of life. I had a very hard time preparing meals and eating them without being in ketosis. I should also qualify that I am no longer taking 12 TBS of coconut oil since being on a low carbohydrate diet. Serum ketone levels are much more responsive to ketone supplementation when on a low carb diet. I am down to 4 TBS per day. Last edited by satwar; 04-16-2014 at 09:38 AM. |
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"Thanks for this!" says: | anagirl (04-16-2014) |
04-17-2014, 06:53 AM | #79 | ||
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Junior Member
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Yes indeed, when I started reading about insulin resistance, it made me start thinking about a possible mechanism for the onset of PD and the failure of the mitochondria to function correctly in producing ATP. Wild speculation but interesting.
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"Thanks for this!" says: | lab rat (04-17-2014) |
04-20-2014, 09:56 AM | #80 | ||
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I am still walking 5 km in 50 minutes, same as last year. We had a viciously bad winter so I'm not walking up to my best yet. I have noticed that in ketosis I breath much easier, and have been introducing intervals of jogging during my walk. Of course that brings my 5 km time down to 40-45 minutes. So I would have to say my 5 km time has actually decreased since being in ketosis.
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