Parkinson's Disease Tulip


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Old 07-05-2012, 07:21 PM #11
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Default Hydrogenated water?

Quote:
Originally Posted by michael7733 View Post
You are so right, but go toward the beginning of the cascade of events tothe uncoupling of t he oxidative phosphorylation process.Two documents were released by the U.S. government in 2009. The first one stated that Agent Orange uncoupled the oxidative phosphorylation process, while the other one stated that the uncoupling of the oxidative phosphorylaion process causes Parkinson's disease. Take a look at what happens here. This is where a hydrogen electron is used to create ATP (energy) .
michael
Not sure if this relates to what you and Rick are discussing but is interesting in that it supports what you are saying about Hydrogen and Mitochondrial dysfunction. It looks like Hydrogen may just be neuroprotective after all.


Hydrogen in Drinking Water Reduces Dopaminergic Neuronal Loss in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine Mouse Model of Parkinson's Disease.


As for the supplement, could it be both a digestive neutralizer improving both the absorption of and thus metabolism of your meds? Maybe that is a given.

Good for you on the results! That sense of normalcy is a rare bird in PD.

Laura
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Old 07-05-2012, 09:40 PM #12
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Default Wow!

That is the first time I have seen that in print outside of what I Have written. YEEEEHAAAAA

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Old 07-06-2012, 07:51 AM #13
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1. Antioxid Redox Signal. 2011 Jul 15;15(2):343-52. Epub 2011 Apr 5.

Inhaled hydrogen sulfide prevents neurodegeneration and movement disorder in a
mouse model of Parkinson's disease.

Kida K, Yamada M, Tokuda K, Marutani E, Kakinohana M, Kaneki M, Ichinose F.

Department of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General
Hospital, Harvard Medical School, Boston, Massachusetts, USA.

Parkinson's disease is one of the major neurodegenerative disorders. Neurotoxin
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) can cause Parkinson's
disease-like symptoms and biochemical changes in humans and animals. Hydrogen
sulfide (H(2)S) has been shown to protect neurons. The goal of this study was to
examine the effects of inhaled H(2)S in a mouse model of Parkinson's disease
induced by MPTP. Male C57BL/6J mice received MPTP at 80 mg/kg and breathed air
with or without 40 ppm H(2)S for 8 h/day for 7 days. Administration of MPTP
induced movement disorder and decreased tyrosine hydroxylase (TH)-containing
neurons in the substantia nigra and striatum in mice that breathed air.
Inhalation of H(2)S prevented the MPTP-induced movement disorder and the
degeneration of TH-containing neurons. Inhaled H(2)S also prevented apoptosis of
the TH-containing neurons and gliosis in nigrostriatal region after
administration of MPTP. The neuroprotective effect of inhaled H(2)S after MPTP
administration was associated with upregulation of genes encoding antioxidant
proteins, including heme oxygenase-1 and glutamate-cysteine ligase. These
observations suggest that inhaled H(2)S prevents neurodegeneration in a mouse
model of Parkinson's disease induced by MPTP, potentially via upregulation of
antioxidant defense mechanisms and inhibition of inflammation and apoptosis in
the brain.

PMCID: PMC3118610 [Available on 2012/7/15]
PMID: 21050138 [PubMed - indexed for MEDLINE]
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Born in 1953, 1st symptoms and misdiagnosed as essential tremor in 1992. Dx with PD in 2000.
Currently (2011) taking 200/50 Sinemet CR 8 times a day + 10/100 Sinemet 3 times a day. Functional 90% of waking day but fragile. Failure at exercise but still trying. Constantly experimenting. Beta blocker and ACE inhibitor at present. Currently (01/2013) taking ldopa/carbadopa 200/50 CR six times a day + 10/100 form 3 times daily. Functional 90% of day. Update 04/2013: L/C 200/50 8x; Beta Blocker; ACE Inhib; Ginger; Turmeric; Creatine; Magnesium; Potassium. Doing well.
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Old 07-06-2012, 11:04 AM #14
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It's all here:

http://www.fightingparkinsonsdrugfre...ng-more-water/
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Old 07-08-2012, 12:55 AM #15
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Default ride that wave!

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Originally Posted by michael7733 View Post
ok, here it is. After 53 continual hours of wonderful, relaxing, restful and focused "ON" time, I went off. It reminded me of the movie Awakenings. I am scheduled to increase the dosage of Mega Hydrate tomorrow, July 5th, 2012. 53 symptom-free hours was much more than I had anticipated. I was blessed.

michael

Hi Michael,

After reading your thread I dug out a royal body care product called "Hydracell" I had that was collecting dust and am considering trying your mega hydrate. This was a tiimely topic for me. I think water is very important to us. Is anyone reading this taking distilled water?
so please tell Michael...how are you doing now?

Thanks for the post
md
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Old 07-08-2012, 01:53 AM #16
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Default Incorrect thinking

After i write this many of you are going to sit there for a mment dumbfounded. At least that is what i did after realizing that i had been thinking incorrectly for most of my life concerning water and food and what happens to them on the way to where they go. hmmmm...an awful thought just hit me...what if i am the only one who thought this way....oh well, here goes.

Think of an egg. cook it and put i t in yout mout h. chew it up. swallow it. is it still an egg. yes it is. now allow it t o get out of y our stomach.what happens to it next? is it still an egg? to some degree it is...sort of. it is being churned and churned until it is unrecognizeable. the process continues, and the "EGg" is no longer an egg. but look at the pictur e in your mind. is it still an egg? lol ...probably so. now part of the churn is being eliminated and part of it continues until it is broken down into tiny building blocks called amino acids.but wait...do you still see an egg...maybe. tust me. t ha t egg is nowhere to be found. The same thing happens t liquids. you have heard it said "You are what you eat? " That isn't quite true. We aren't even what we absorb completely. We are what we assimmilate. We need to understand this before we continue.

michael
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Old 07-08-2012, 02:24 PM #17
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Default Beginning detoxification process

It hurts, but it is a necessary step.

Quote:
Hi Michael,

After reading your thread I dug out a royal body care product called "Hydracell" I had that was collecting dust and am considering trying your mega hydrate. This was a tiimely topic for me. I think water is very important to us. Is anyone reading this taking distilled water?
so please tell Michael...how are you doing now?
md, I normally have between 10 and 14 "ON" hours per day, but they are rarely symptom free. Of the 80 consecutive hours that followed 9:30 a.m. JUly 3rd, 2012, 77 of them were symptom free. This was sgnificant. Now I am entering the detoxificat ion stage, so...well...that is another story. I am expecting better things in the near future.

Muireanne,

I do wish that it could be that easy.. Obviously, we do benefit greatly by drinking good amounts of clean, polution free water, but it,too, must be broken down before it is assimilated for use by the body. Actually, water is a by-product of ATP production in the mitochondria.

Rick and Laura,

I find it interesting that both H(2)S and H(2)0 have that extra hydrogen electron. It makes me wonder if ionized air would be beneficial and neuro protective. We should look into that.

michael
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Old 07-08-2012, 02:54 PM #18
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Quote:
Originally Posted by michael7733 View Post
Most of us have not reached the age of retirement yet, and we are dependent upon one or more forms of disability income, There are literally millions of us across the globe who fit into this category. Ha ve you ever asked yourself what you will do for income when a cure is found? We will probably be asked to give up our disability incomes and rejoin the workforce. I know that most of yu do not believe that a cure will come in your lifetime, and you could be right...or...you could be wrong.
Five days ago I added a supplement to my daily regimen of Sinemet and Requip. On day one, June 29, 2012, I took 2 capsules of Mega Hydrate. I think I had a little more energy that day, but it didn't seem t o be a significant amount. On day 2 I forgot to take them. I remembered on days 3, 4 and 5. Today is July 3rd, 2012, day 5. I have divided my medication into 5 doses during the day, and I usually get 2 to 3 hours of "ON" time from each dose. I usually go "OFF" about an hour to an hour and a half before my next dose is due. There is a 9 hour space of time between my last dose of the day and the first dose of the next day. During my "OFF" times, I am pretty much dependent on my motorized scooter to get around. Shuffling, rigidity and freezing are in control during those times. As of right now, 2:40 PM, July 3rd, 2012, I have been "ON" for 29 straight hours with no rigidity, no freezing and no shuffling. I consider this to be significant.
I am not saying that this is a cure or even a new area to look in for a treatment. I am not even saying that this supplement caused this to happen. I am say ing that , to me, this is significant.
michael

I am so blessed
any success is great, I say keep up the meds. I watch my father in-law suffer for years, trying everything under the sun. I wish you the very best.
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Old 07-08-2012, 04:19 PM #19
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Quote:
Originally Posted by moondaughter View Post
I noticed longer "on" times with drinking rain water....am considering trying an experiment with distilled water.
Rick have you considered coconut water?? - chock full of bioavailable potassium, magnesium and calcium.

md
I have tried coconut milk and not even that seems to snap me back to normal. It does seem to shorten the length of the paralytic episode, but so does sugar...?

MD, where do you get potable rain water?


Laura
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Old 07-08-2012, 05:33 PM #20
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Re-enter the workplace? Yes, I do think about this--rather frequently, I would say. I even wonder if OUR combined thoughts on this matter have some effect on whether or not a "cure" comes to pass. I have heard it said that--WE call forth whatever WE fear. Then the question becomes--do WE fear going back to work more (or less) than living/dieing with/from PD? Ultimately--is OUR fear of going back to work the only real thing that's preventing a cure?...or, is OUR fear of living (dieing) with PD the only thing preventing a cure? Either way, it seems like a double-whammy.
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