Anyone have experience with enzyme therapy? In particular I am referring to a product by "NOW" which they call "Plant Enzymes." About a dozen diferent ones blended. Many familiar names such as bromelain, papain, lactase, amylase, etc.

I started taking it yesterday morning because my wife made me as a common sense move given my diet. It had nothing to do with PD in my mind. But by yesterday afternoon I began to notice that I seemed to be doing better and by the time I went to bed at midnight there was no denying it.

So today I have been paying attention and there is no question. My functional ability is up by 25% and my sinemet intake is down by a third! Anyone have a clue out there?

-Rick

something similar to grapefruit inhibiting enzymes that might break down l-dopa
ron started similar thread

Naturally occurring compounds may also induce or inhibit CYP activity. For example, bioactive compounds found in grapefruit juice and some other fruit juices, including bergamottin, dihydroxybergamottin, and paradicin-A, have been found to inhibit CYP3A4-mediated metabolism of certain medications, leading to increased bioavailability and, thus, the strong possibility of overdosing.[15] Because of this risk, avoiding grapefruit juice and fresh grapefruits entirely while on drugs is usually advised.[16]

http://neurotalk.psychcentral.com/ar.../t-161250.html

http://web.archive.org/web/200308290...ML/000855.html

http://web.archive.org/web/200308290...ML/000858.html

http://web.archive.org/web/200308290...ML/000898.html

http://web.archive.org/web/200308290...ML/000908.html

http://web.archive.org/web/200308290...ML/000934.html

http://web.archive.org/web/200306071...ML/003504.html

http://web.archive.org/web/200308290...ML/000990.html

Well, that is as far as I got when i realized that the information on enzymes could and does fill volumes. It's a start.

michael