Parkinson's Disease Tulip


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Old 08-17-2012, 07:12 PM #1
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Default Pygeum

Has anyone had any experience with this one? African tree bark used for prostate problems. Picked some up yesterday and it seems to work as advertised. But, I swear, it seems to have an effect on my PD as well. I've been jumpy all day and I think that I skipped a pill or two. Hardly scientific, I know. But still.... About 90 papers at PubMed but all on prostates.
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Born in 1953, 1st symptoms and misdiagnosed as essential tremor in 1992. Dx with PD in 2000.
Currently (2011) taking 200/50 Sinemet CR 8 times a day + 10/100 Sinemet 3 times a day. Functional 90% of waking day but fragile. Failure at exercise but still trying. Constantly experimenting. Beta blocker and ACE inhibitor at present. Currently (01/2013) taking ldopa/carbadopa 200/50 CR six times a day + 10/100 form 3 times daily. Functional 90% of day. Update 04/2013: L/C 200/50 8x; Beta Blocker; ACE Inhib; Ginger; Turmeric; Creatine; Magnesium; Potassium. Doing well.
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Old 08-18-2012, 04:35 PM #2
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Default It's a stretch...

I always enjoy a good research challenge but was about to give up. It's helpful that my long-term memory is still intact.

Pygeum is a phyto-sterol and a precursor to the anabolic steroid known as Boldenone. The latter is made for use by veterinarians but not surprisingly professional sports players dope with it. Here is the neurology connection; Boldenon stimulates release of erythropoietin and that is now in research proving to be neuroprotective in a number of contexts including PD.

Here is a link explaining all potential benefits. I know this isn't exactly the same thing but it is definitely a building block to the steroid so this could be key to its protective properties..

Erythropoietin: a multimodal neuroprotective agent


Incidentally, our good friend Amgen has multliple patents on a compound with a basis that was used to treat anemia in Cancer patients.
of Erthropoietin.

Laura
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