FAQ/Help |
Calendar |
Search |
Today's Posts |
08-23-2012, 09:18 PM | #1 | ||
|
|||
Senior Member
|
Based on a study of 1762 PwP in Korea, Lee et al. [1] used the concept of L-dopa equivalent daily dose (LEDD, see [2]) to offer some insights into regional differences in the doses of drugs that people are taking.
Average LEDD Korea 608.9 mg Germany 599.2 mg Average LEDD immediately before DBS: Japan 419.5 mg Taiwan 788.8 - 899.9 mg Europe 808.5 mg North America 1074 - 1409 mg These differences were despite the fact that disease duration and UPDRS scores were similar. LEDD on average increased during the first 10 years of the disease, but then plateaued. Reference [1] "Daily dose of dopaminergic medications in Parkinson disease: Clinical correlates and a posteriori equation" 1Jee-Young Lee MD, 2Jae Woo Kim MD PhD, 3Won Yong Lee MD PhD, 4Jong-Min Kim MD PhD, 5Tae-Beom Ahn MD PhD, 6Han-Joon Kim MD, 3Jinwhan Cho MD PhD, 6Beom S Jeon MD PhD Neurology Asia 2010; 15(2) : 137 – 143 http://www.neurology-asia.org/articles/20102_137.pdf [2] http://neurotalk.psychcentral.com/thread169655.html John
__________________
Born 1955. Diagnosed PD 2005. Meds 2010-Nov 2016: Stalevo(75 mg) x 4, ropinirole xl 16 mg, rasagiline 1 mg Current meds: Stalevo(75 mg) x 5, ropinirole xl 8 mg, rasagiline 1 mg |
||
Reply With Quote |
Reply |
|
|
Similar Threads | ||||
Thread | Forum | |||
Professor's ALS drug safe in sizable doses | ALS News & Research |