Parkinson's Disease Tulip


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Old 09-04-2012, 10:15 AM #1
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Default SPRITE- to help bioavailability?

http://www.sciencedaily.com/releases...1013124330.htm

I found this article to be interesting and I think I'll give it a try with my meds for a couple of days. It makes me laugh to think of drinking this in the morning instead of my usual green tea with local organic honey and wisconsin ginseng! Kind of like Woody Allen's movie "Sleeper", where woodster wakes up a thousand years after being frozen to find that junk food is now the new health food.

Soft Drink Could Enhance Effects of an Anti-Cancer Drug

ScienceDaily (Oct. 14, 2010) — Experiments with an artificial stomach suggest that a popular lemon-lime soft drink could play an unexpected role in improving the effectiveness of an oral anticancer drug. The experiments produced evidence that patients will absorb more of the unnamed drug, tested in Phase I in clinical trials, when taken with "flat" or degassed Sprite.

The study appears in ACS' Molecular Pharmaceutics.

Faraj Atassi and colleagues note that efforts are underway to develop more anticancer medications that patients can take by mouth. However, biological variations among patients -- due to variations in stomach acidity and other factors -- can reduce the effectiveness of oral anticancer drugs. Such was the case with the unnamed anticancer drug in the study, identified only as "Compound X." There were wide differences in how the drug was absorbed in the first patients who took it.

The scientists combined Compound X with Captisol, a substance that helps improve the solubility of drug ingredients, and turned to the artificial stomach. That glass-and-plastic device is used to study how drugs and foods dissolve through the GI tract. They showed that Sprite seemed to control stomach acidity in a way likely to allow greater absorption of the drug into the body. Based on the results, the scientists suggest that patients in future clinical trials take the drug with Sprite.
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Old 09-04-2012, 04:01 PM #2
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Default As if Big Pharma wasn't enough

...now we have to worry about Big Bubbley too.
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Born in 1953, 1st symptoms and misdiagnosed as essential tremor in 1992. Dx with PD in 2000.
Currently (2011) taking 200/50 Sinemet CR 8 times a day + 10/100 Sinemet 3 times a day. Functional 90% of waking day but fragile. Failure at exercise but still trying. Constantly experimenting. Beta blocker and ACE inhibitor at present. Currently (01/2013) taking ldopa/carbadopa 200/50 CR six times a day + 10/100 form 3 times daily. Functional 90% of day. Update 04/2013: L/C 200/50 8x; Beta Blocker; ACE Inhib; Ginger; Turmeric; Creatine; Magnesium; Potassium. Doing well.
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Old 09-05-2012, 03:50 PM #3
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Anyone tried this ? Does this work ?
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