FAQ/Help |
Calendar |
Search |
Today's Posts |
12-01-2012, 01:28 PM | #1 | |||
|
||||
Senior Member
|
Lewy pathology out of favor as Parkinson’s culprit
Published on November 30, 2012 http://www.news-medical.net/news/201...s-culprit.aspx By Eleanor McDermid, Neurodegeneration and cellular dysfunction may precede the appearance of Lewy bodies in the substantia nigra, shows research that challenges the role of Lewy pathology in Parkinson's disease (PD). "This report may help to change the view on Lewy pathology," Walter Schulz-Schaeffer (University Medical Center Göttingen, Germany) writes in an editorial accompanying the study in Neurology. The study, considered together with other recent findings and the clinical effectiveness of dopamine-replacement therapy, "leaves little doubt that the degenerative process must be located at the presynapse," he says... ...Schulz-Schaeffer says: "We should disengage from the notion of Lewy body-associated cell death as the main phenomenon in PD and concentrate on synaptic pathology and axonal degeneration of still-existing cells in our search for therapy and for understanding the pathophysiology of PD."
__________________
In the last analysis, we see only what we are ready to see, what we have been taught to see. We eliminate and ignore everything that is not a part of our prejudices. ~ Jean-Martin Charcot The future is already here — it's just not very evenly distributed. William Gibson |
|||
Reply With Quote |
"Thanks for this!" says: | Conductor71 (12-05-2012), lurkingforacure (12-01-2012) |
Reply |
|
|
Similar Threads | ||||
Thread | Forum | |||
New Culprit for Parkinson’s? | Parkinson's Disease | |||
Parkinson's disease and immune system: is the culprit LRRKing in the periphery? | Parkinson's Disease | |||
Narcolepsy, Parkinson's Disease, and Lewy Body Dementia | Parkinson's Disease |