I was wondering if anyone else here has had issues with muscle twitching. I have recently reduced my sinemet dosage to alleviate dyskinesia and the twitching has gotten much worse. I have always had them to some degree but now when I sit in a chair and have a pair of shorts on I can actually see the muscles going crazy. It feels and even looks like something is running around under my skin. I don't know if the worsening of this is a result of sinemet reduction or just disease progression. Thanks

Let's make sure that we're talking about the same thing: my fasciculations are irregular movements of parts of a muscle (in my case almost entirely the calf muscle). You can feel the movement, but it is not painful. There is no movement of the limb.

I first noticed these in 1986. I saw a doctor, who sent me for a blood test (I can't remember for what), and was told there's nothing to worry about.

When I was in the process of being diagnosed for PD, I told the neurologist, and was told the same thing.

They've continued ever since, never causing a problem.

But since diagnosis in 2005, I've often wondered if they are linked to PD.

See
http://thetheoryofmediocrity.blogspo...of-benign.html
for an interesting blog on the subject.

John

I have had the exact same experience as John T

Thanks JohnT it does sound like we are talking about the same thing. There is no limb movement nor any pain, although as I sit and watch this going on in my legs it sometimes leads to painful cramps. Good to hear two different doctors say it is not a serious concern. But as you said I have to believe its pd related