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04-22-2013, 08:09 AM | #1 | |||
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Mov Disord. 2013 Apr 2. doi: 10.1002/mds.25405. [Epub ahead of print]
The relationship between balance control and vitamin D in Parkinson's disease-a pilot study. Peterson AL, Mancini M, Horak FB. Source Parkinson's Center of Oregon, Oregon Health and Science University, Portland, Oregon, USA; Parkinson's Disease Research and Education Center, Portland Veterans Affairs Hospital, Portland, Oregon, USA. Abstract BACKGROUND: Balance problems and falls are a major source of morbidity and mortality in patients with Parkinson's disease. Vitamin D supplementation reduces falls and sway in neurologically intact elderly fallers, but effects in Parkinson's disease are not established. METHODS: To study this relationship and select outcome measures for a vitamin D intervention study, balance function and vitamin D concentration were quantified in a series of Parkinson's patients in a cross-sectional, observational study. Participants underwent a battery of 5 balance tests. RESULTS: Serum vitamin D concentrations were correlated inversely with Parkinson's severity, as measured by the motor Unified Parkinson's Disease Rating Scale. Among the balance measures, vitamin D concentrations were correlated with automatic posture responses to backwards translation, specifically with response strength and stance weight asymmetry. CONCLUSIONS: These findings support the hypothesis that vitamin D plays a role in balance among patients with Parkinson's disease and identify specific outcome measures for detecting effects of vitamin D upon balance. © 2013 Movement Disorder Society. Copyright © 2013 Movement Disorder Society. PMID: 23554003 [PubMed - as supplied by publisher] (I am unable to assess if this study is meaningful. Not enough information about the trial. Though studies in elderly with low Vit D levels and increased incidence of falls gives me much pause.)
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"Thanks for this!" says: | MeAndPD (04-22-2013), VICTORIALOU (04-23-2013) |
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