Parkinson's Disease Tulip


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Old 05-09-2013, 08:48 PM #1
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Default Folate and vitamin B12 levels in levodopa-treated Parkinson's disease patients

Parkinsonism Relat Disord. 2008;14(4):321-5. Epub 2007 Dec 4.
Folate and vitamin B12 levels in levodopa-treated Parkinson's disease patients: their relationship to clinical manifestations, mood and cognition.
Triantafyllou NI, et al
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Athens University Medical School, Athens, Greece.
Abstract
We tested the hypothesis that mood, clinical manifestations and cognitive impairment of levodopa-treated Parkinson's disease (PD) patients are associated with vitamin B12 and folate deficiency. To this end, we performed this cross-sectional study by measuring serum folate and vitamin B12 blood levels in 111 consecutive PD patients. Levodopa-treated PD patients showed significantly lower serum levels of folate and vitamin B12 than neurological controls, while depressed patients had significantly lower serum folate levels as compared to non-depressed. Cognitively impaired PD patients exhibited significantly lower serum vitamin B12 levels as compared to cognitively non-impaired. In conclusion, lower folate levels were associated with depression, while lower vitamin B12 levels were associated with cognitive impairment. The effects of vitamin supplementation merit further attention and investigation.
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Old 05-10-2013, 12:04 PM #2
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Default Thiamine and b12

Thank you for that article . I often wondered about that. I take H2 blockers which block the absorption of those vit. Suppose supplement is in order.
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