Parkinson's Disease Tulip


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Old 09-20-2013, 04:42 AM #1
lab rat lab rat is offline
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Default Interesting abstract on another potential PD therapy

http://brain.oxfordjournals.org/cont...24.short?rss=1
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Old 09-20-2013, 06:54 AM #2
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Default A good find

Ursolic acid-
ursocholanic acid-

From- Brain (2013) doi: 10.1093/brain/awt224
Ursocholanic acid rescues mitochondrial function in common forms of familial Parkinson’s disease -
"... Of 15 compounds, two were chosen for subsequent functional studies, namely ursocholanic acid and the related compound dehydro(11,12)ursolic acid lactone. Both compounds markedly increased the activity of all four complexes of the mitochondrial respiratory chain. The naturally occurring compound ursolic acid and the licensed drug ursodeoxycholic acid are chemically closely related to ursocholanic acid and dehydro(11,12)ursolic acid lactone. All four substances rescue mitochondrial function to a similar extent ...."


From- Science Daily June 7, 2011
Apple Ingredient Keeps Muscles Strong: Component of Apple Peels Found to Help Prevent Muscle Weakening in Mice
"....The researchers next gave ursolic acid to fasted mice. Those experiments showed that ursolic acid could protect against muscle weakening as predicted. When ursolic acid was added to the food of normal mice for a period of weeks, their muscles grew. Those effects were traced back to enhanced insulin signaling in muscle and to corrections in the gene signatures linked to atrophy....."


Common in the body building world, here are some sources.=
http://epharmnutrition.com/ursobolic.php

http://www.amazon.com/s?ie=UTF8&page...ursolic%20acid

Note that this seems to be the herb known as "holy basil" (very common)

Talk to your doc first but it seems to be a slam dunk.


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Originally Posted by lab rat View Post
__________________
Born in 1953, 1st symptoms and misdiagnosed as essential tremor in 1992. Dx with PD in 2000.
Currently (2011) taking 200/50 Sinemet CR 8 times a day + 10/100 Sinemet 3 times a day. Functional 90% of waking day but fragile. Failure at exercise but still trying. Constantly experimenting. Beta blocker and ACE inhibitor at present. Currently (01/2013) taking ldopa/carbadopa 200/50 CR six times a day + 10/100 form 3 times daily. Functional 90% of day. Update 04/2013: L/C 200/50 8x; Beta Blocker; ACE Inhib; Ginger; Turmeric; Creatine; Magnesium; Potassium. Doing well.
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Old 10-06-2013, 10:43 AM #3
badboy99 badboy99 is offline
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