This latest chapter began a couple of weeks back when I had become concerned with the erratic nature of my med response. One of the basic possibilities was that diabetes was creeping up on me. In the course of my research I came across info about the use of apple vinegar to drastically lower the glycemic index of ones' meal. This then led to the discovery of work that found that vinegars had properties that made them an ACE inhibitor completely independently of their glucose management abilities. ACE inhibitors are good for PWP because of their effect on mitochondria.

Still with me boys and girls? So here is the heart of the matter, at least for tonight. Starting about a week ago, I revisited some related work that Laura and I had explored about temporary paralysis that results from an interaction between insulin, potassium, and magnesium. I had shelved it back then due to concerns about potassium overdose. Overblown in most cases, my GP had OK'd up to 20 Molar units daily in my investigation of the possibilities in my own case. For a number of reasons I put it on hold.

Until last week, when I took another look at the file. I began taking magnesium citrate and potassium gluconate and guickly worked up to the previous targets.

Right away I could tell that something was going on. The fluctuations that had started me on this road were gone. I was taking less medication with levodopa/carbidopa down to about 600 mg today from about 2000 mg two weeks ago. And I am getting stronger, esp in my legs. Plus a decade long problem with constipation is much improved.

But all is not roses. There was a bit of dyskinesia at first, mostly in the evening. And, here is the big one, if I don't keepan eagle eye on the dosing I get mad as a hatter for about three hours or so around dinner time! I have had some illlicit affairs with various chemicals over the years so I know a little whereof I speak and I would describe it as being loopy as a git. I am aware of my actions and whereabouts and I pose no dangers to self or small mammals, but there is no denying that I am flat on my ***.

But why? Any ideas?