http://medicalxpress.com/news/2014-0...ng-easier.html

Sitting for prolonged periods of time—with little muscular contraction occurring—shuts off a molecule called lipoprotein lipase, or LPL, Sara Rosenkranz said. Lipoprotein lipase helps to take in fat or triglycerides and use it for energy.

"We're basically telling our bodies to shut down the processes that help to stimulate metabolism throughout the day and that is not good," Sara Rosenkranz said. "Just by breaking up your sedentary time, we can actually upregulate that process in the body."

In a previous study published in the International Journal of Behavioral Nutrition and Physical Activity, the researchers found that the more people sit, the greater their chances of obesity, diabetes, cardiovascular disease and overall mortality.