Parkinson's Disease Tulip


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Old 12-23-2013, 10:40 PM #1
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Default Another miracle? Levodopa, Hyperglycemia, Vinegar, and PD

Follow me for a minute if you will. It has been known for ninety years that levodopa causes an increase in blood sugar in rabbits and, presumably, in humans as well. If true, then we get a spike in our blood sugar everytime we take a levodopa/carbodopa tablet. I have no reason to think that a similar reaction occurs with agonists or other drugs, but that simply leaves the issue open.

Assuming that the effect is limited to those of us who depend on L/C, that means that many, if not most, of us will walk into the problem at some point in our patient careers and will experience the sudden rush of insulin flooding our systems, the surge and retreat of glucose being sucked out of our blood and into the muscle cells, the similar movement of potassium out of reach that can turn us into zombies, the imbalance as we confront a similar movement of magnesium, the action of the kidneys as they attempt to fill their role in the balancing act by concentrating urine and peeing away excess water, the resulting loss of large numbers of water soluble B-vitamins and minerals leading to dehydration, ....you get the picture.

With this way of looking at things, everytime you take a sinemet or generic you are setting off a very unpleasent cascade of events that may ultimately do you in.

There is a possible solution that I began fooling around with today. With the holidays rushing at us so quickly, let me suggest an easy experiment for you. I tried it this afternoon twice and am amazed at the results.

Just take a teaspoon or two of vinegar each time you take levodopa.

There is indeed a reaction of some bbsort that causes the food that is eaten by a diabetic to drop in the glycemic index by approximately 50%. The assumption has been that whatever action might exist that it was related to the food consumed but that is not proven.

I suspect that the excitement for PWP is over at the Insulin end of the bar and that the diabetic patients who have been trying to figure this out have done us a great favor.

Try it. Not with your food but with your sinemet.
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Born in 1953, 1st symptoms and misdiagnosed as essential tremor in 1992. Dx with PD in 2000.
Currently (2011) taking 200/50 Sinemet CR 8 times a day + 10/100 Sinemet 3 times a day. Functional 90% of waking day but fragile. Failure at exercise but still trying. Constantly experimenting. Beta blocker and ACE inhibitor at present. Currently (01/2013) taking ldopa/carbadopa 200/50 CR six times a day + 10/100 form 3 times daily. Functional 90% of day. Update 04/2013: L/C 200/50 8x; Beta Blocker; ACE Inhib; Ginger; Turmeric; Creatine; Magnesium; Potassium. Doing well.
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Old 12-26-2013, 04:34 PM #2
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I'll try it again cuz I luvs Vinegar anyway. Sounds interesting.

Kinda like the guy that told me about a cure for badly chapped lips. "You rub a Rabbit dropping on your lips. Medically, no benefit but you sure don't lick your lips as much".
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Old 12-27-2013, 06:10 PM #3
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Default Vinegar, what kind? ( Apple Cider, white, etc..?

What kind of vinegar should I use for this experiment? I'm not diabetic, would this still work?
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Old 12-27-2013, 09:24 PM #4
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Default how taken

For better absorption, I try to take sinemet on an empty stomach. Adding two teaspoons of vinegar to this seems an invitation for gastric trials & tribulations. Dr. Jarvis' 1970's book A Vermont Doctor's Guide to Good Health recommended honey with vinegar. What's your approach? And what kind? Apple cider vinegar, white or Japanese rice wine vinegar (Mirin)?

Jon
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Old 12-27-2013, 09:29 PM #5
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Quote:
Originally Posted by aquario View Post
For better absorption, I try to take sinemet on an empty stomach. Adding two teaspoons of vinegar to this seems an invitation for gastric trials & tribulations. Dr. Jarvis' 1970's book A Vermont Doctor's Guide to Good Health recommended honey with vinegar. What's your approach? And what kind? Apple cider vinegar, white or Japanese rice wine vinegar (Mirin)?

Jon
Trials & Trib's for sure. When I swallow, I make sure I'm standing next to "Plam B".
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Old 01-01-2014, 04:30 PM #6
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Default What amazing result did you get?

When you started taking the vinegar, what was the result? Did the sinemet work faster, longer, no dyskinesia, etc.?




Quote:
Originally Posted by reverett123 View Post
Follow me for a minute if you will. It has been known for ninety years that levodopa causes an increase in blood sugar in rabbits and, presumably, in humans as well. If true, then we get a spike in our blood sugar everytime we take a levodopa/carbodopa tablet. I have no reason to think that a similar reaction occurs with agonists or other drugs, but that simply leaves the issue open.

Assuming that the effect is limited to those of us who depend on L/C, that means that many, if not most, of us will walk into the problem at some point in our patient careers and will experience the sudden rush of insulin flooding our systems, the surge and retreat of glucose being sucked out of our blood and into the muscle cells, the similar movement of potassium out of reach that can turn us into zombies, the imbalance as we confront a similar movement of magnesium, the action of the kidneys as they attempt to fill their role in the balancing act by concentrating urine and peeing away excess water, the resulting loss of large numbers of water soluble B-vitamins and minerals leading to dehydration, ....you get the picture.

With this way of looking at things, everytime you take a sinemet or generic you are setting off a very unpleasent cascade of events that may ultimately do you in.

There is a possible solution that I began fooling around with today. With the holidays rushing at us so quickly, let me suggest an easy experiment for you. I tried it this afternoon twice and am amazed at the results.

Just take a teaspoon or two of vinegar each time you take levodopa.

There is indeed a reaction of some bbsort that causes the food that is eaten by a diabetic to drop in the glycemic index by approximately 50%. The assumption has been that whatever action might exist that it was related to the food consumed but that is not proven.

I suspect that the excitement for PWP is over at the Insulin end of the bar and that the diabetic patients who have been trying to figure this out have done us a great favor.

Try it. Not with your food but with your sinemet.
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Old 01-01-2014, 06:01 PM #7
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Default My apologies

My apologies to all for dropping this but my family had the misfortune to have one of its younger members unexpectedly lose a two-year battle with ovarian cancer just after my last post and the fire has not been there. I will gradually get it back together.

If I recall correctly, the main thing that had my interest was a sense of stability that I didn't have before. It was pretty vague and I was really trying to encourage others to try it since it was both cheap and safe. lifeus interruptus


Quote:
Originally Posted by Brainstorm View Post
When you started taking the vinegar, what was the result? Did the sinemet work faster, longer, no dyskinesia, etc.?
__________________
Born in 1953, 1st symptoms and misdiagnosed as essential tremor in 1992. Dx with PD in 2000.
Currently (2011) taking 200/50 Sinemet CR 8 times a day + 10/100 Sinemet 3 times a day. Functional 90% of waking day but fragile. Failure at exercise but still trying. Constantly experimenting. Beta blocker and ACE inhibitor at present. Currently (01/2013) taking ldopa/carbadopa 200/50 CR six times a day + 10/100 form 3 times daily. Functional 90% of day. Update 04/2013: L/C 200/50 8x; Beta Blocker; ACE Inhib; Ginger; Turmeric; Creatine; Magnesium; Potassium. Doing well.
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Old 01-01-2014, 06:15 PM #8
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Quote:
Originally Posted by reverett123 View Post
My apologies to all for dropping this but my family had the misfortune to have one of its younger members unexpectedly lose a two-year battle with ovarian cancer just after my last post and the fire has not been there. I will gradually get it back together.

If I recall correctly, the main thing that had my interest was a sense of stability that I didn't have before. It was pretty vague and I was really trying to encourage others to try it since it was both cheap and safe. lifeus interruptus
So sorry to for your loss. Passing should be exclusively for old guys like me that have lived thier time and then some.
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Old 01-02-2014, 09:23 AM #9
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Quote:
Originally Posted by reverett123 View Post
My apologies to all for dropping this but my family had the misfortune to have one of its younger members unexpectedly lose a two-year battle with ovarian cancer just after my last post and the fire has not been there. I will gradually get it back together.

If I recall correctly, the main thing that had my interest was a sense of stability that I didn't have before. It was pretty vague and I was really trying to encourage others to try it since it was both cheap and safe. lifeus interruptus

My sincere sympathy to you and your family. May you find comfort in memories and love.
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Old 01-06-2014, 03:53 PM #10
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So sorry to hear of your loss ...may the Lord comfort your family.
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