Parkinson's Disease Tulip


advertisement
Closed Thread
 
Thread Tools Display Modes
Old 05-20-2007, 03:22 PM #21
Daffy Duck's Avatar
Daffy Duck Daffy Duck is offline
ex-Member
 
Join Date: Sep 2006
Posts: 110
15 yr Member
Daffy Duck Daffy Duck is offline
ex-Member
Daffy Duck's Avatar
 
Join Date: Sep 2006
Posts: 110
15 yr Member
Default

Vicky, when somebody abandons the issue due to running out of evidence and instead attempts to falsely criticise the person they disagree with, then it can only be assumed to be a personal attack.
Daffy Duck is offline  

advertisement
Old 05-20-2007, 03:53 PM #22
kimmydawn's Avatar
kimmydawn kimmydawn is offline
Senior Member
 
Join Date: Sep 2006
Location: Ohio
Posts: 3,455
15 yr Member
kimmydawn kimmydawn is offline
Senior Member
kimmydawn's Avatar
 
Join Date: Sep 2006
Location: Ohio
Posts: 3,455
15 yr Member
Default

There have been some personal attack due to strong opinion on this thread. It's been removed.

Please keep responses to the orginal topic *without flaming another*.

If you have a personal issue with another member's comments on the thread, please send a PM.

Thanks!

KD
__________________
<center>
.

From the caterpillar emerged
~Strong in flight, beautiful to the eyes, movement laced with grace~
The butterfly
**KD**
</center>

Last edited by kimmydawn; 05-20-2007 at 04:06 PM. Reason: typo
kimmydawn is offline  
Old 05-20-2007, 09:25 PM #23
pdinfo pdinfo is offline
In Remembrance
 
Join Date: Apr 2007
Posts: 31
15 yr Member
pdinfo pdinfo is offline
In Remembrance
 
Join Date: Apr 2007
Posts: 31
15 yr Member
Default Perhaps this may add something to this discussion

http://www.youtube.com/watch?v=_9MY0bbO0qw
pdinfo is offline  
Old 05-21-2007, 03:12 AM #24
Teretxu's Avatar
Teretxu Teretxu is offline
Member
 
Join Date: Sep 2006
Location: Asturias, Spain
Posts: 172
15 yr Member
Teretxu Teretxu is offline
Member
Teretxu's Avatar
 
Join Date: Sep 2006
Location: Asturias, Spain
Posts: 172
15 yr Member
Default

Quote:
Originally Posted by Daffy Duck View Post
If stress was the REAL cause of Parkinson's Disease, then the most stressed of people would have Parkinson's Disease but they don't.

Persistent famines, warfare, dire poverty, lawlessness, severe malnutrition, is what the Ethiopians have to deal with, yet Ethiopians have the world's LOWEST prevalence of Parkinson's Disease.

The lowest prevalence of Parkinson's Disease in Europe is amongst the Bulgarian Gypsies yet they have the greatest amount of stress to deal with due to their high crime rates, poverty, ill health, malnutrition, and grossly inadequate healthcare and social services.

The biochemical fault that has persistently been found to coincide with Parkinson's Disease is the low levels of the enzymes required for the formation of dopamine. Stress does not affect these enzyme levels at all.

L-dopa can potently relieve symptoms of Parkinson's Disease due to its ability to form dopamine. Due to also being the precursor of adrenaline, L-dopa has the capacity to increase stress. If the theory was right L-dopa would increase symptoms, but it does the opposite.

So the claim that stress is the REAL cause of Parkinson's Disease is plainly inconsistent with the facts.

Acetylcholine increases muscle contraction. Dopamine reduces muscle contraction. Parkinson's Disease occurs when there is not enough dopamine to counter the effect of increased muscle contraction.

The reason why there appears to be a coincidence between stress and Parkinsons' Disease symptoms is that when somebody is stressed they produce adrenaline. Adrenaline increases the effect of acetylcholine and thereby temporarily increases Parkinson's Disease symptoms due to increasing muscle contraction.

So rather than stress being the cause of Parkinson's Disease, stress merely exacerbates Parkinson's Disease symptoms.
Daffy, I don't know about Ethiopians, but I do know about gypsies, and let me tell you: they are the world's leaststressed out community!!! There's no way in the world a gypsy will get PD if the cause is stress. They follow no one's rules but their own, to the point that many do not send their kids to school, because they have to get up so early. I have a friend who's an elementary school teacher in a part of town with a large gypsy population and the average absentee rate is above 60%. At the beginning she tried to pick up the smaller kids at home and drive them to school herself, but she soon gave up when the mothers very politely and tenderly assured her that getting up at 8 o'clock was too soon for the little ones. You will find many playgrounds full of gypsy children during school hours, who run off when they see the Police approaching (school attendance is mandatory for everyone's children under 16). I'm not judging anybody, just telling it like it is, and having said this, I believe gypsies are right in their vital attitudes, only today's Society will cast out anyone who doesn't play by the rules. So, you either bend or break...only trouble is that you can also break from bending too much!
Teretxu is offline  
Old 05-21-2007, 05:14 AM #25
Daffy Duck's Avatar
Daffy Duck Daffy Duck is offline
ex-Member
 
Join Date: Sep 2006
Posts: 110
15 yr Member
Daffy Duck Daffy Duck is offline
ex-Member
Daffy Duck's Avatar
 
Join Date: Sep 2006
Posts: 110
15 yr Member
Default Gypsy Duck

Follow no one's rules but their own. Don't like getting up early. Never stressed. Think that school's a waste of time.

I reckon I must have Gypsy ancestry.
Daffy Duck is offline  
Old 05-21-2007, 08:15 AM #26
aftermathman aftermathman is offline
Member
 
Join Date: Sep 2006
Location: Evesham, England
Posts: 598
15 yr Member
aftermathman aftermathman is offline
Member
 
Join Date: Sep 2006
Location: Evesham, England
Posts: 598
15 yr Member
Default Living in Evesham I both know gypsies ...

and see them every day, (not Bulgarian gypsys I grant you).

They live in and around Evesham due to the high amount of agricultural work on offer.

Given the relationship between PD and pesticides, agricultural insecticides, etc, shouldn't gypsy PD incidence be high ?

Daffy, given your last comments re. gypsys, I hope you are not planning to get a new drive anytime soon.

Neil.
aftermathman is offline  
Old 05-21-2007, 08:27 AM #27
reverett123's Avatar
reverett123 reverett123 is offline
In Remembrance
 
Join Date: Aug 2006
Posts: 3,772
15 yr Member
reverett123 reverett123 is offline
In Remembrance
reverett123's Avatar
 
Join Date: Aug 2006
Posts: 3,772
15 yr Member
Default Some relevant works (Gould)

1: Leuner B, Mirescu C, Noiman L, Gould E.
Maternal experience inhibits the production of immature neurons in the
hippocampus during the postpartum period through elevations in adrenal steroids.
Hippocampus. 2007 Mar 30;17(6):434-442 [Epub ahead of print]
PMID: 17397044 [PubMed - as supplied by publisher]

2: Mirescu C, Peters JD, Noiman L, Gould E.
Sleep deprivation inhibits adult neurogenesis in the hippocampus by elevating
glucocorticoids.
Proc Natl Acad Sci U S A. 2006 Dec 12;103(50):19170-5. Epub 2006 Nov 29.
PMID: 17135354 [PubMed - indexed for MEDLINE]

3: Stranahan AM, Khalil D, Gould E.
Social isolation delays the positive effects of running on adult neurogenesis.
Nat Neurosci. 2006 Apr;9(4):526-33. Epub 2006 Mar 12.
PMID: 16531997 [PubMed - indexed for MEDLINE]

4: Mirescu C, Gould E.
Stress and adult neurogenesis.
Hippocampus. 2006;16(3):233-8. Review.
PMID: 16411244 [PubMed - indexed for MEDLINE]

5: Kozorovitskiy Y, Gould E.
Dominance hierarchy influences adult neurogenesis in the dentate gyrus.
J Neurosci. 2004 Jul 28;24(30):6755-9.
PMID: 15282279 [PubMed - indexed for MEDLINE]

6: Mirescu C, Peters JD, Gould E.
Early life experience alters response of adult neurogenesis to stress.
Nat Neurosci. 2004 Aug;7(8):841-6. Epub 2004 Jul 25.
PMID: 15273691 [PubMed - indexed for MEDLINE]

7: Coe CL, Kramer M, Czeh B, Gould E, Reeves AJ, Kirschbaum C, Fuchs E.
Prenatal stress diminishes neurogenesis in the dentate gyrus of juvenile rhesus
monkeys.
Biol Psychiatry. 2003 Nov 15;54(10):1025-34.
PMID: 14625144 [PubMed - indexed for MEDLINE]

8: Kozorovitskiy Y, Gould E.
Adult neurogenesis: a mechanism for brain repair?
J Clin Exp Neuropsychol. 2003 Aug;25(5):721-32. Review.
PMID: 12815508 [PubMed - indexed for MEDLINE]
__________________
Born in 1953, 1st symptoms and misdiagnosed as essential tremor in 1992. Dx with PD in 2000.
Currently (2011) taking 200/50 Sinemet CR 8 times a day + 10/100 Sinemet 3 times a day. Functional 90% of waking day but fragile. Failure at exercise but still trying. Constantly experimenting. Beta blocker and ACE inhibitor at present. Currently (01/2013) taking ldopa/carbadopa 200/50 CR six times a day + 10/100 form 3 times daily. Functional 90% of day. Update 04/2013: L/C 200/50 8x; Beta Blocker; ACE Inhib; Ginger; Turmeric; Creatine; Magnesium; Potassium. Doing well.
reverett123 is offline  
Old 05-21-2007, 02:00 PM #28
rosebud's Avatar
rosebud rosebud is offline
Member
 
Join Date: Aug 2006
Location: Great Green Pacific Rainforest
Posts: 488
15 yr Member
rosebud rosebud is offline
Member
rosebud's Avatar
 
Join Date: Aug 2006
Location: Great Green Pacific Rainforest
Posts: 488
15 yr Member
Default 2 cents worth

Stress is relative...it's not what happens to us, but how we respond. There is clearly an element of individuality that plays a key role. The central questions in my mind are: who are we really? What is the meaning of life? I feel like I suffer from Post Traumatic Stress Disorder, and life would have been a whole lot more do-able if I were made out of rubber! (the really hard Indian kind that those balls we had as kids were made of...they bounced like crazy!) ...well the girls had them anyway. I personally, am highly suspicious of the PD label. But not having had any other serious illness, I don't know that I wouldn't have the same suspicious attitude toward whatever dis-ease was upon me. "Like seeing through a glass darkly" ....love that phrase Paul uses to describe this life. Oh, I've used up my 2 cents...damn! I was just getting started!
__________________
I would never die for my beliefs because I might be wrong. Bertrand Russell
rosebud is offline  
Old 05-21-2007, 02:30 PM #29
vlhperry's Avatar
vlhperry vlhperry is offline
Member aka Dianna Wood
 
Join Date: Oct 2006
Posts: 736
15 yr Member
vlhperry vlhperry is offline
Member aka Dianna Wood
vlhperry's Avatar
 
Join Date: Oct 2006
Posts: 736
15 yr Member
Default Stress is not relative

When cortisal rises and genetic mutations can be found in the Parkin gene you bet we are affected by stress. Many of us probably respond by trying to control how we react to stress by not exposing it by losing our temper, but because we practice self control, cortisal levels do not fall and Parkin mutations do not disappear. call it what you want, but the stress does phsyciologically exist.

My two cents,
Vicky
vlhperry is offline  
Old 05-21-2007, 03:28 PM #30
Ibken Ibken is offline
Member
 
Join Date: Aug 2006
Posts: 243
15 yr Member
Ibken Ibken is offline
Member
 
Join Date: Aug 2006
Posts: 243
15 yr Member
Default It's in the Mix...

I agree with Rosebud. It's not the stress - or any other contributing factor per se, but in how the individual responds to it. In Ayurveda, PD is considered a Vata disorder. My type is mainly Vata. There are lots of sites that provide little quizzes to determine your Dosha - type. And there are lots of other ways of classing bio-whatever types.

Whatever creates the huge unrelenting demand for dopamine in our bodies is the 'cause' of PD . After a while we can't keep up with the demand as it eventually exceeds our capacity to supply it....voila! symptoms! Physical trauma, emotional issues, stress of any & all kinds, illness, mean people, dirtry air, war, etc, ...

There are a lot of ways out there to help with all these things...and I am always on the lookout.

WE need a pd motel where we can meet and figure it all out and get some healing herapies while we're there. Really. There needs to be a PD Patient Healing Gathering Place.....

Sweet Dreams...Ibby
Ibken is offline  
Closed Thread


Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is Off


Similar Threads
Thread Thread Starter Forum Replies Last Post
God Is Real Jennifer Sanctuary for Spiritual Support 4 01-09-2007 10:44 AM
No burning on a real hot day. Brian Peripheral Neuropathy 24 12-15-2006 10:34 PM
Trying real hard to get through this dreambeliever128 Reflex Sympathetic Dystrophy (RSD and CRPS) 6 12-04-2006 10:18 PM
the real mgh chat clouds z Social Chat 3 09-30-2006 03:00 PM


All times are GMT -5. The time now is 05:58 AM.

Powered by vBulletin • Copyright ©2000 - 2024, Jelsoft Enterprises Ltd.

vBulletin Optimisation provided by vB Optimise v2.7.1 (Lite) - vBulletin Mods & Addons Copyright © 2024 DragonByte Technologies Ltd.
 

NeuroTalk Forums

Helping support those with neurological and related conditions.

 

The material on this site is for informational purposes only,
and is not a substitute for medical advice, diagnosis or treatment
provided by a qualified health care provider.


Always consult your doctor before trying anything you read here.