[Bob Dawson]

There is no stopping this now. Thanks, Ben et al.

http://www.nytimes.com/2014/02/03/op...ple.html?&_r=1

Give the Data to the People

By HARLAN M. KRUMHOLZFEB. 2, 2014

New York Times

LAST week, Johnson & Johnson announced that it was making all of its clinical trial data available to scientists around the world. It has hired my group, Yale University Open Data Access Project, or YODA, to fully oversee the release of the data. Everything in the company’s clinical research vaults, including unpublished raw data, will be available for independent review.

This is an extraordinary donation to society, and a reversal of the industry’s traditional tendency to treat data as an asset that would lose value if exposed to public scrutiny.

Today, more than half of the clinical trials in the United States, including many sponsored by academic and governmental institutions, are not published within two years of their completion. Often they are never published at all. The unreported results, not surprisingly, are often those in which a drug failed to perform better than a placebo. As a result, evidence-based medicine is, at best, based on only some of the evidence. One of the most troubling implications is that full information on a drug’s effects may never be discovered or released.

Even when studies are published, the actual data are usually not made available. End users of research — patients, doctors and policy makers — are implicitly told by a single group of researchers to “take our word for it.” They are often forced to accept the report without the prospect of other independent scientists’ reproducing the findings — a violation of a central tenet of the scientific method….

…. There are many benefits to this kind of sharing. It honors the contributions of the subjects and scientists who participated in the research. It is proof that an organization, whether it is part of industry or academia, wants to play a role as a good global citizen. It demonstrates that the organization has nothing to hide. And it enables scientists to use the data to learn new ways to help patients. Such an approach can even teach a company like Johnson & Johnson something it didn’t know about its own products.

For the good of society, this is a breakthrough that should be replicated throughout the research world.

Harlan M. Krumholz is a professor of cardiology and public health at the Yale School of Medicine.

[pegleg]

J&J is a pretty size able compNy. I hope the other biggies follow their lead in releasing this data. I was pleased when I read this, but a
Ways a bit unbelieving until I see things starting to happen.