Parkinson's Disease Tulip


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Old 08-15-2014, 10:24 AM #1
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Default FORBES BLOG: Why Parkinson's Disease Is So Scary: No Cause, No Cure. But It's Not A K

pd is getting a lot of attn to say the least.
just a few incorrect tidbits in the apparently quickly researched article


http://www.forbes.com/sites/dandiamo...-not-a-killer/
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Old 08-15-2014, 11:06 AM #2
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pd is getting a lot of attn to say the least.
just a few incorrect tidbits in the apparently quickly researched article


http://www.forbes.com/sites/dandiamo...-not-a-killer/
In the meantime, Parkinson’s patients can rely on new and emerging treatments, like deep brain stimulation (pictured below) and complex drug regimens, to help slow down their symptoms.

I wish I knew what all these NEW AND EMERGING treatments were......
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Old 08-15-2014, 05:38 PM #3
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Default Emerging therapies for Parkinson's disease: From bench to bedside

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Originally Posted by Tupelo3 View Post
In the meantime, Parkinson’s patients can rely on new and emerging treatments, like deep brain stimulation (pictured below) and complex drug regimens, to help slow down their symptoms.

I wish I knew what all these NEW AND EMERGING treatments were......
There is an "article in press" - Emerging therapies for Parkinson's disease: From bench to bedside, a highlight to most recent advances in the pharmacological and non-pharmacological treatments of PD.

Full text available at - http://web.as.uky.edu/Biology/faculty/cooper/Gamma%20knife-Nuclear%20medicine/Emerging%20therapies%20for%20Parkinson's%20disease .pdf

Department of Psychiatry and Neuroscience Program, Harvard Medical School, McLean Hospital, Belmont, MA 02478, USA; The Pharmaceutical Research Institute at Albany College of Pharmacy and Health Sciences, Rensselaer, NY 12144, USA; School of Medicine, American University of Beirut, Beirut, Lebanon
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Old 08-16-2014, 11:07 AM #4
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There is an "article in press" - Emerging therapies for Parkinson's disease: From bench to bedside, a highlight to most recent advances in the pharmacological and non-pharmacological treatments of PD.


[I]
Thanks WXXU, that's a good summary review, although I think they left out a few drugs that are probably closer to approval.

I sort of made my original comment rhetorically "tongue in cheek". However, after reading the article, I now can say it more emphatically, "where are all of the emerging treatments". The review clearly shows that, although there is a lot of interesting research going on, and there has been a lot of in-vitro and animal model success, there is no new emerging treatment on the near horizon. Outside of Safinamide (which will likely get approval within a year), what drug did they mention that is likely to be approved for general use within the next year? Two years? Five years? Even with Safinamide, I don't think we can call it "new and emerging". It's another MAO-B inhibitor that clearly shows successful results, but was never tested against rasagiline or selegiline. So, we really don't know if this is just another "me-too" or it is actually an improvement.

I personally still feel very confident that we will see breakthrough emerging treatments down the road. However, maybe Forbes should do a little bit of research on the true current state before rushing to put out an article.

Last edited by Tupelo3; 08-16-2014 at 09:25 PM.
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Old 08-17-2014, 04:26 PM #5
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Thanks WXXU, that's a good summary review, although I think they left out a few drugs that are probably closer to approval.

I sort of made my original comment rhetorically "tongue in cheek". However, after reading the article, I now can say it more emphatically, "where are all of the emerging treatments". The review clearly shows that, although there is a lot of interesting research going on, and there has been a lot of in-vitro and animal model success, there is no new emerging treatment on the near horizon. Outside of Safinamide (which will likely get approval within a year), what drug did they mention that is likely to be approved for general use within the next year? Two years? Five years? Even with Safinamide, I don't think we can call it "new and emerging". It's another MAO-B inhibitor that clearly shows successful results, but was never tested against rasagiline or selegiline. So, we really don't know if this is just another "me-too" or it is actually an improvement.

I personally still feel very confident that we will see breakthrough emerging treatments down the road. However, maybe Forbes should do a little bit of research on the true current state before rushing to put out an article.
Whether is another "me-too" or a very limited improvement, I personally think as a patient, the count of new drugs (for each class) is simply not that important to us. Because by the end of the day your eyes are on those really work best for the most...
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