FAQ/Help |
Calendar |
Search |
Today's Posts |
09-02-2014, 04:35 AM | #1 | ||
|
|||
Member
|
|
||
Reply With Quote |
"Thanks for this!" says: | aab45 (09-10-2014), badboy99 (09-02-2014), GerryW (09-02-2014), johnt (08-30-2018), soccertese (09-02-2014), Stand Tall (09-10-2014), Tupelo3 (09-02-2014) |
09-02-2014, 08:58 AM | #2 | ||
|
|||
Magnate
|
thanks, interesting work, will take awhile to read and digest.
will have compare to early controlled release research. haven't read enough of article to see if they measured "on/off" or if patients were advanced enough to experience them. |
||
Reply With Quote |
09-02-2014, 09:03 AM | #3 | |||
|
||||
Member
|
Interesting! On the other hand psyllium (Metamucil, plantago) is not recommended for PWP because it can make constipation worse. See http://movementdisorders.ufhealth.or...-constipation/
The article contradicts itself by first recommending Metamucil then warning against it.
__________________
Born 1948. Diagnosed 2011. DBS ON 7/17. Taking cd/ld 200 MG at 6 am, 9 am, 12 pm, 3 pm, 6 pm and 9 pm. Finasteride 5 mg, Life Extension Mix and Once-Daily Health Booster, Mitochondrial Energy Optimizer with BioPQQ, Optimized Curcumin (longvida), Triple Action Cruciferous Vegetable Extract with Resveratrol, Vectomega-3, Vit D3 5000U,Lithium orotate 5 mg, AMPK Activator, Kefiran, N-Acetyl-L- Cysteine (NAC), Tri-Magnesium, Advanced NeuroPro, Duozyme, Palmitoylethanolamide (PEA) Updated 9/21/17. |
|||
Reply With Quote |
"Thanks for this!" says: |
09-02-2014, 09:36 AM | #4 | ||
|
|||
Member
|
Quote:
Last edited by Tupelo3; 09-03-2014 at 07:02 AM. |
||
Reply With Quote |
"Thanks for this!" says: | lab rat (09-02-2014) |
09-02-2014, 11:00 PM | #5 | ||
|
|||
Senior Member
|
So we'll see, and report back. I will be curious to see if it has any effect on
1. constipation (does it help in that dept. or make things worse or have no effect) 2. evening out the peaks/valleys of dosing every two hours just a note: the one I bought from a health food store is a capsule of pure psyllium....there are others that have a bunch of other stuff in them. I wanted to avoid that complicating factor so we went with the pure encapsulated version. Best to take the capsule with a full 8oz. of water, I was told...I guess if you don't do that, you can increase the chance of getting constipated. |
||
Reply With Quote |
"Thanks for this!" says: | lab rat (09-03-2014) |
09-10-2014, 08:33 AM | #6 | ||
|
|||
Member
|
Although I can’t speak about flaxseed helping smooth out levodopa absorption levels, it is however an excellent and healthy way to help alleviate and/or prevent the discomfort of constipation.
I have used flaxseed for over a decade, adding it to everything thing from oatmeal, cereals, yogurt, smoothies, baked goods, meatloaf, meatballs, etc. Be sure to use ground flaxseed (whole seeds will not be absorbed) and refrigerate the open package. Give it a try, add 1-2 tablespoons to your diet, slowly. It has a nutty flavor, much nicer than the “orange” drink! http://www.mayoclinic.org/healthy-li...d/faq-20058354 http://www.webmd.com/diet/features/benefits-of-flaxseed |
||
Reply With Quote |
"Thanks for this!" says: |
08-30-2018, 06:49 PM | #7 | ||
|
|||
Senior Member
|
I'm still looking for ways to smooth out levodopa levels. And via the original paper, found this thread from 4 years ago.
Here are the pharmacokinetic parameters reported in the paper: V = value U = units A = initial situation B = Plantago ovata husk P = placebo V, U, A, B, P TMAX, min, 35.83, 39.72, 36.17 CMAX, ng/ml, 603.2, 547.8, 612.0 AUC, ug.min/ml, 62.87, 64.47, 65.10 THALF, min, 75.2, 81.9, 74.0 So, any effect here is small and probably not statistically significant. But, nevertheless, it's probably a useful area for N=1 trials: you might be able to squeeze a 10% increase out of your levodopa by optimising its use in this way. John
__________________
Born 1955. Diagnosed PD 2005. Meds 2010-Nov 2016: Stalevo(75 mg) x 4, ropinirole xl 16 mg, rasagiline 1 mg Current meds: Stalevo(75 mg) x 5, ropinirole xl 8 mg, rasagiline 1 mg |
||
Reply With Quote |
Reply |
|
|
Similar Threads | ||||
Thread | Forum | |||
Smooth Gator | Reflex Sympathetic Dystrophy (RSD and CRPS) | |||
Magnesium absorbtion/amount and Kaprex? | Vitamins, Nutrients, Herbs and Supplements | |||
PD & smooth muscles - & heart problems... | Parkinson's Disease | |||
Smooth Away - Product Review | Women's Health | |||
Low B12 with absorbtion problems | Vitamins, Nutrients, Herbs and Supplements |