FAQ/Help |
Calendar |
Search |
Today's Posts |
11-09-2014, 06:01 PM | #1 | ||
|
|||
Member
|
Looks like intranasal delivery of Stem Cells works great!
The promising findings, reported in Rejuvenation Research, a peer-reviewed journal published by Mary Ann Liebert, Inc. highlight the potential for a noninvasive approach to cell therapy delivery in Parkinson disease-a safer and effective alternative to surgical transplantation of stem cells. www.sciencedaily.com/releases/2011/02/110208163504.htm |
||
Reply With Quote |
11-09-2014, 08:02 PM | #2 | ||
|
|||
Senior Member
|
This article is dated almost three years ago, in February of 2011. I wonder why there does not seem to be any follow up or newer work in this?
|
||
Reply With Quote |
11-09-2014, 09:56 PM | #3 | ||
|
|||
Member
|
It is always the same reason, MONEY. Too many promising projects stop at preclinical studies because it is difficult to get funds for clinical studies.
|
||
Reply With Quote |
"Thanks for this!" says: | violet green (11-09-2014) |
11-10-2014, 08:56 AM | #4 | ||
|
|||
New Member
|
Is it because they've run out of money, or might it be because the drug companies do not want cures to be discovered for some diseases????? When something looks to be as promising as this intranasal GDNF, if it truly were the money... what about a foundation such as the Michael J. Fox Foundation picking up where the study left off?? I am very apprehensive... think there may just be a whole lot more to promising studies dead ends that what the general public is aware...
|
||
Reply With Quote |
11-10-2014, 10:58 AM | #5 | ||
|
|||
Magnate
|
Quote:
there are 2 or more GDNF trials in progress, there has been a huge amount of research on gdnf and some very large and expensive trials in the past that failed treating pd, one funded by AMGEN, search on GDNF here. everything seems to cure/prevent pd in rats but fails miserably in humans. money is an issue but so is finding enough volunteers willing to risk introducing drugs and/or genes into the brain when pd isn't fatal, that is also slowing down the pace of research. every gene therapy trial in humans has failed yet worked great in rodents and primates. gotta keep things in perspective. if you want to get involved join PAN or some other advocacy group. |
||
Reply With Quote |
11-10-2014, 11:09 AM | #6 | ||
|
|||
Member
|
Quote:
Last edited by zanpar321; 11-10-2014 at 12:10 PM. |
||
Reply With Quote |
11-10-2014, 11:39 AM | #7 | ||
|
|||
Member
|
Quote:
Amgen sued for Parkinson's drug http://www.bizjournals.com/losangele...5/daily29.html Last edited by zanpar321; 11-10-2014 at 02:30 PM. |
||
Reply With Quote |
"Thanks for this!" says: | Betsy859 (11-11-2014) |
11-10-2014, 11:51 AM | #8 | ||
|
|||
Member
|
|
||
Reply With Quote |
11-10-2014, 12:03 PM | #9 | ||
|
|||
Member
|
Quote:
So, instead, we have the research for PD and other less prevalent diseases left to smaller biotech companies, and there are actually many of them doing great research. However, their funds tend to be limited and this leads to extended timelines for getting drugs approved. Ultimately, we see Big Pharma stepping in at the end, when the drug is close to approval and has been de-risked, and just buying out the smaller biotech. It's a lot simpler model for Pharma than doing their own research. Still, with all of the above being said, the number one reason for delays in the clinical trial process is finding participants to volunteer. If PWP want to make a real difference, they need to be more willing to step into the line of fire and participate in trials. |
||
Reply With Quote |
11-10-2014, 12:22 PM | #10 | ||
|
|||
Member
|
Quote:
Last edited by zanpar321; 11-10-2014 at 01:48 PM. |
||
Reply With Quote |
Reply |
|
|
Similar Threads | ||||
Thread | Forum | |||
Dramatic improvement of parkinsonian symptoms after gluten-free diet... | Parkinson's Disease | |||
A Phase 1 Study of Intranasal Reduced Glutathione in Parkinson's Disease | Parkinson's Disease | |||
Intranasal Delivery of Stem Cells to Rat Brains | Parkinson's Disease | |||
Intranasal delivery of GDNF | Parkinson's Disease | |||
New Treatment For Parkinson's Disease Shows Dramatic Results in First Study: | Parkinson's Disease |