My wife has Parkinson’s disease that was diagnosed in May 2007 and now has twisting movements of severe dyskinesias. Taking carbidopa/levodapa (C/L )25/100 two tablets every 4 hours. Once a day taking 1mg Azilect and a 6mg Neupro patch.
Generally getting 2hours or less of good time after the C/L takes effect. After that having intense pain that lasts many of the times until the next C/L dosage takes effect. Extreme muscle contractions for 1 to 1.5 hours that feel crushing(happens in legs, abdomen, shoulders, neck, intestines – not all at the same time but many times in combination). Spending around 9 hours or more in this pain every 24 hours. Husband massages these various areas to get some temporary relief and walking around sometimes helps. Been to see neurologist and emergency room twice and no one gets the intensity of the twisting and pain. We have not been given anything for these painful times. We need help and need it now because we are unable to continue much longer.