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06-10-2007, 07:26 PM | #1 | |||
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Oral festination in Parkinson's disease: Biomechanical analysis and correlation with festination and freezing of gait.
Parkinson Research Foundation Monday, 04 June 2007 http://www.parkinsonresearchfoundati...d=669&Itemid=1 http://www.ncbi.nlm.nih.gov/sites/en...&dopt=Abstract In Parkinson's disease (PD), festination corresponds to a tendency to speed up when performing repetitive movements. First described in gait (and then in handwriting and speech), festination is one of the most disabling axial symptoms. To establish the phenomenology of oral festination (OF) and the condition's potential links with other axial disorders, we submitted a simple, rhythmic, repetitive, vocal motor task to 40 PD patients and 20 controls. Forty-five percent of the 40 patients presented OF, which was strongly associated with gait festination but not with the severity of freezing of gait (FOG) or dysarthria. With respect to the two pathophysiological hypotheses that have been put forward, a possible link with tremor (as previously suggested in tapping) was not confirmed in this study and so, in view of the significant increase in variability observed, we conclude that OF shares the same pathophysiology as gait disorders.
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