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03-19-2015, 02:27 PM | #1 | ||
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So, I've just discovered that I have mutations on the MTHFR gene - at C677T and A1298C. Very interesting! My GP thinks this could one of possibly many reasons why I have PD, especially at such a young age (diagnosed at 38).
He has suggested I start taking Tyrosine and Methyl Folate every day, along with a little 5HTP and Glutathione. This should help aid my body in the processes that my body should be performing but isn't, due to these mutations. I also tested for a few B- vitamins, after all the discussions here about B's. They all came out in the normal range - interestingly B-1 came out high. I just emailed my Neurologist - waiting to hear back. Does any one else have these mutations? |
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03-19-2015, 05:05 PM | #2 | ||
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Junior Member
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B12 levels: U.S. standards may be too low It is important to check MMA blood levels and supplement with B12 where needed http://www.medicalcompassmd.com/b12-...ndards-may-be/ |
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03-19-2015, 06:06 PM | #3 | ||
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"Thanks for this!" says: | anagirl (03-19-2015) |
03-20-2015, 01:10 AM | #4 | |||
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Grand Magnate
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Anagirl, has your doctor checked your blood homocysteine level?
It can be abnormally high in people with the C677T and/or A1298C mutations of the MTHFR gene. Abnormally high blood homocysteine is associated with a condition called homocystinuria which can have a number of adverse health effects. If your blood homocysteine level is abnormally high your doctor will be able to discuss the implications of that with you. |
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03-20-2015, 10:18 AM | #5 | ||
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Thank you for this! I had read about it online and my Dr did discuss it with me. We are going to try this supplement protocol for a bit and then do more testing. I have also read that Sinemet can increase homocysteine... not a good mix for someone with these mutations! One step forward two steps back. |
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03-20-2015, 10:18 PM | #6 | |||
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Senior Member
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My husband (PWP) is homozygous for MTHFR C677T( possesses both risk alleles for this SNP).
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"Thanks for this!" says: | anagirl (03-22-2015) |
03-22-2015, 04:39 PM | #7 | ||
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I'm heterozygous a1298c and have many more mutations that interfere with methylation. I know other pwps with mthfr.
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"Thanks for this!" says: | anagirl (03-22-2015) |
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