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04-16-2015, 08:11 PM | #11 | ||
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Junior Member
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Getting the right dosage is important for all drugs. However, my experience so far is that for Rytary it is crucial. It also is very tricky to achieve. I wondered why Impax came out with so many variations of Rytary. Now I understand.
I started out taking 3 caps of 48.75MG-195MG 3 times a day (at 6am-12pm-6pm). This led to daytime dyskinesia, wearing-off and sleepless nights. After trying additional modifications, I'm currently taking 2 caps of 48.75-195MG combined with one cap of 36.25-145MG at 6am and 10:30am followed by one cap of 48.75MG-195MG combined with two caps of 36.25-145MG at 5pm and bedtime. I'm also taking 100mg of Amantadine twice a day. This combination seems to be working, but I'm guessing that it will be a continuing process to get the dosage right as symptoms change. Rytary is a great drug, although getting my insurance company to agree to pay for it with a reasonable co-pay is a battle. |
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04-16-2015, 10:43 PM | #12 | ||
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Junior Member
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Quote:
I am also very happy with rytary. The first dosage schedule my MDS was 3 capsules of 195 MG ever 4 hrs at 6AM. 10, 2 and 6PM. But after about 3 weeks I had some minor wearing off in the late afternoon about 4-5PM so I switched to the alternate schedule my MDS provided which was 3 capsules ever 3 hrs at 6AM, 9, Noon and 3 PM then 1 capsule at 6PM which is 1 more capsule then the 1st schedule (13 capsules/day vice 12) and very slightly exceeds the FDA max dosage/day of 2450MG. This alternate schedule seems to be working better with no wearing off. I have not had any problems at night with 12 hrs from my last dose at 6PM to my first dose the next morning at 6AM. Slumpy |
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04-17-2015, 07:40 AM | #13 | ||
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Magnate
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boy, that sure seems odd it doesn't work during the night. have you contacted IMPAX labs about that? |
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04-17-2015, 08:41 AM | #14 | ||
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Senior Member
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That's really strange, and makes us not too interested in trying this drug |
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08-26-2015, 05:23 PM | #15 | ||
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Newly Joined
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Could be that it has something to do with burst/clean contractions that occur both during fasting, and especially at night. Rytary is a player in digestion, and digestion stops while the intestine self-cleans. I'm not a medical pro, but I'd look at the digestion difference as a clue to the absorption difference. Do a search on gi motility |
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