Impax on its Rytary web page has recommended prescribing information for
conversion for folks who have been on carbidopa/levodopa

AND
a second recommendation for folks who have not been on carbidopa/levodopa.

check it out

I would look up meds on other drug information websites as well as the "brand" name site.. Just to get a well rounded view of it.

http://www.rxlist.com/rytary-drug/si...teractions.htm

http://www.drugs.com/sfx/rytary-side-effects.html

http://forum.parkinson.org/index.php...ytary-rabound/

he reports some patients have done worse. i know C/L controlled release can do that to, i assume it just doesn't dissolve under certain circumstances?

i wonder if food is more a factor, i'm not referring to protein interference but would food slow down passage thru the small intestine a little and help/hurt?

My husband has been on Rytary for approximately 30 days. His experience has been good but we are still adjusting. He started taking 2 at 195 four times a day but that was continuous DYSK. He is now on 3x145 four times a day. His 'on' time is much improved...sometimes even getting 5 hours between doses but when it wears off, it is gone...there seems to be no half life. We try not to eat for an hour before or after dosing whether protein or not. Seems to take 45-60 minutes to kick in. Sleep is much improved. We have an appointment with the Neurologist next week and we are anxious to learn how her other patients are doing on the drug.

Would love to have more feedback from others taking the drug.

This is my 40th day on Rytary (3-47.85/195MG capsules 4 times/day, every 4 hrs starting at 6AM) and I have recently had some moderate wearing off in afternoons around 4-5PM that lasts until my 6PM dose kicks in (I take 3 capsules at 2PM and my last 3 of the day at 6PM). Tomorrow I'm going to try an alternate dosing schedule my MDS gave me were I take 3 capsules every 3 hrs starting at 6AM then 9AM, Noon and 3PM with a single capsules at 6PM. We'll see how it goes. I have found that for me Rytary is very sensitive to when I eat (especially if my meal is high protein) My MDS recommended I wait 1 hr after taking Rytary for meals and it appears he was correct.

Slumpy

just curious, are you "on" when you wake up and if not, how long does it take for your first dose of the day to kick in?

can you compare rytary to sinemet CR or a combo of sinemet IR/CR which some people take, for example 100mg IR + 200mg CR every 3 to 4 hours.

Yes, I'm on when I wake up even though I took my last dose of Rytary ay 6PM but I usually wake at 6AM and immediatly take me first dose of Rytary. I only used IM 25/100 and I feel that Rytary works better and I don't have to take it as often.

Slumpy

I wanted to report on my mom's experience with this, which unfortunately was not positive. It gave her very bad dyskinesias (worse than with Sinemet and Sinemet CR) and did not provide improved relief. It also made her sleep even worse.

We're disappointed this didn't work, and still looking for the next step, which I hope will be to try to significantly reduce Sinemet and try a different dopamine substance in its place. Sinemet gives her had side effects like debilitating shortness of breath. I am aware that reducing Sinemet can be dangerous and we would proceed with great caution.

I hope that those of you who have had a good initial experience with Rytary continue to experience improvement. It seems to be helping many people.