Parkinson's Disease Tulip


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Old 05-20-2015, 02:32 PM #1
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Default Uric acid relates to dopamine transporter availability in Parkinson's disease

http://www.ncbi.nlm.nih.gov/pubmed/25288358
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Old 05-20-2015, 03:06 PM #2
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Lower levels of uric acid appear to associated with PD in these studies.

http://bmjopen.bmj.com/content/3/11/e003620.short

http://jpet.aspetjournals.org/content/324/1/1.full

A smaller study published last year also suggested that high uric acid levels could slow the progression of Parkinson’s Disease.

http://www.telegraph.co.uk/news/heal...sufferers.html
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Old 05-20-2015, 03:07 PM #3
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Default higher uric acid + different gut bacteria =?

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This is interesting, and raises the thought that perhaps we should be looking at connections between the things we do know. For example, we know PWP have higher levels of uric acid in their blood AND a (recently discovered) substantially different mix of gut bacteria than nonPWP. How could these conditions be related? What might the combination of these two factors mean? Has anyone studied the gut biome of PWP whose uric acid measured in the high range, and if so, what were the findings? I think we could learn a lot more meaningful things about PD if we started looking at the relationships between the things we do know, now.
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Old 05-20-2015, 04:07 PM #4
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Originally Posted by lurkingforacure View Post
This is interesting, and raises the thought that perhaps we should be looking at connections between the things we do know. For example, we know PWP have higher levels of uric acid in their blood AND a (recently discovered) substantially different mix of gut bacteria than nonPWP. How could these conditions be related? What might the combination of these two factors mean? Has anyone studied the gut biome of PWP whose uric acid measured in the high range, and if so, what were the findings? I think we could learn a lot more meaningful things about PD if we started looking at the relationships between the things we do know, now.
Exactly Lurking! I have begun a compilation of things we know about PD earlier this year, things we think we know and additional things we would like to know. I hope to compile this in the next few months.
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Old 05-20-2015, 07:10 PM #5
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Originally Posted by lurkingforacure View Post
This is interesting, and raises the thought that perhaps we should be looking at connections between the things we do know. For example, we know PWP have higher levels of uric acid in their blood AND a (recently discovered) substantially different mix of gut bacteria than nonPWP. How could these conditions be related? What might the combination of these two factors mean? Has anyone studied the gut biome of PWP whose uric acid measured in the high range, and if so, what were the findings? I think we could learn a lot more meaningful things about PD if we started looking at the relationships between the things we do know, now.
I believe PWP have lower levels of UA generally.
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Old 05-20-2015, 07:13 PM #6
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Inosine raises your UA.
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