Parkinson's Disease Tulip


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Old 09-22-2015, 08:21 PM #8
johnt johnt is offline
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Join Date: Apr 2009
Location: Stafford, UK
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johnt johnt is offline
Senior Member
 
Join Date: Apr 2009
Location: Stafford, UK
Posts: 1,059
15 yr Member
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Gerry,

You write:

"I currently take 34.5 g of Mucuna (40% levodopa) daily plus 45 g of tyrosine."

That's approximately 14g of levodopa per day, plus whatever may come from the tyrosine. This compares with for most people on C/L of under 1g (= 1000mg) per day.

I think it would be really useful to everyone if we understood why these numbers are so different.

For a start, you don't take carbidopa. Wikipedia states that [1]:

"Carbidopa reduces the amount of levodopa required to produce a given response by about 75% ..."

That reduces the comparable level from 14g to approximately 3g.

Are there any other corrections to make?

How do you avoid nausea with these amounts of levodopa?

Reference:

[1] https://en.wikipedia.org/wiki/Carbidopa

John
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Born 1955. Diagnosed PD 2005.
Meds 2010-Nov 2016: Stalevo(75 mg) x 4, ropinirole xl 16 mg, rasagiline 1 mg
Current meds: Stalevo(75 mg) x 5, ropinirole xl 8 mg, rasagiline 1 mg
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