Parkinson's Disease Tulip


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Old 09-23-2015, 07:03 PM #12
anon122822
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anon122822
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Originally Posted by CTjeff View Post
Day 3 update.

The protocol does give relief of symptoms but only for 1-1.5hr max. Then the off effects seem to be worse than when on stalevo.

After alerting his Dr. She recommended him to up the intake of Mucuna d5 to 8 pills per dose. However still the effectiveness has only increased about half an hour to an hr.

On the second day he started developing dyskinesia in his legs which has been very uncomfortable for him. We left a message with his Dr. About this new condition.

So far this protocol has been very difficult for him but is hoping things will turn around when he gets the regimen dialed in.
The average time for how long it takes for a parkinsons patient to get narrowed in on the levels of the nutrients for symptomatic alleviation, as I have read in their studies/website, is around 3-6 months. So understand that it will take a while and at first while transferring from the meds to the amino acids side effects are rather pronounced while the transfer takes place.

”Novel observations reporting a group of 17 Parkinson’s disease patients led to identification of carbidopa-induced dyskinesias, which had not been documented prior to 2012.1 These patients had been ingesting prescribed concomitant l-dopa/carbidopa preparations for 1–7 years. Their drugs were continued as the core nutrients were started. The mean daily dosing value of l-dopa/carbidopa was 1,000 mg and 250 mg, respectively, at the initiation of the core nutrients. The mean duration of previous drug treatment was 3 years, 7 months. Onset of dyskinesias began within the first week of treatment when the core nutrients were added. Dyskinesias were generally described as facial twitching and head bobbing due to peripheral muscle-control problems within the neck and upper shoulders. When dyskinesias developed, the l-dopa/carbidopa was immediately discontinued and the nutritionally sourced l-dopa increased fivefold to compensate for the loss of the carbidopa effect on the central nervous system by blocking peripheral conversion of l-dopa to dopamine. This conversion to higher-dose l-dopa was monitored using the previously published pill-stop technique.37 Following this protocol, all patients achieved full resolution of dyskinesias within 4 days. This led to the hypothesis that the dyskinesias that resolved after applying the new protocol had been induced by the carbidopa and were not related to the l-dopa. There were no refractory dyskinesias experienced.”

Source - http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4238750/
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CTjeff (09-23-2015)
 


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