Parkinson's Disease Tulip


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Old 10-01-2006, 10:08 AM #1
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Default CERE-120 Phase II trials fall of 2006

For people who are avoiding dbs and looking for a treatment that may provide neuroregeneration -- watch for the upcoming the CERE-120 phase II gene therapy multi-center trial coming later this fall of 2006.

They use neurturin -- a neurotrophic factor. Phase I safety trial was a success, and details will be published soon.

ceregene press releases

about phase I

pdf presentation of phase I study design


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Old 10-01-2006, 05:04 PM #2
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Default Jeanb, can you expand on the comment that

Phase 1 was a success ?

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Old 10-01-2006, 10:17 PM #3
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Default Cere-120 Phase I a success

Yes it was a success - I dialed in for an FDA webcast where ceregene presented results of phase I and also generally outlined their plans for phase II. Full details of the Phase I trial will be published (or presented - can't remember which) this month - October 2007. It sounds very promising.

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Old 10-01-2006, 10:23 PM #4
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Default webcast site

Neither the webcast nor the minutes are linked yet - but i think they will be eventually. The meeting took place 9/20/06

This link goes to the web page where you will (eventually) see the link to the webcast about cere-120 phase I and plans for phase II.

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Old 10-02-2006, 01:58 AM #5
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Default Jeanb, thats great news, thankyou

for a good start to my day.

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Old 10-02-2006, 03:25 AM #6
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Default notes on ceregene meeting at NIH

Removed as author was worried about accuracy or misinterpretation, but do try to watch it when it comes online- it was quite interesting watching the questioning and defending of this trial. The trial has champions; wheras the Amgen champion of GNDF passed away of a heart attack. Watching this made me wonder how well it was defended.

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Old 10-02-2006, 09:26 AM #7
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Smile hope

Cere-120 gives me hope for a neurorestorative treatment.

Yes, it's truly a pity about GDNF (which we're still fighting for). But hopefully cere-120 (neurturen) will fill that void for most of us.

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