| FAQ/Help |
| Calendar |
| Search |
| Today's Posts |
07-10-2016, 03:18 AM
|
#11 | ||
|
|||
|
Senior Member
|
Hikoi, to whom my thanks, has posted on the Parkinson's Movement/HealthUnlocked forum that the initial results of the latest GDNF trial have been reported [1]:
"Phase 2 clinical trial evaluating the safety and efficacy of glial cell line-derived neurotrophic factor (GDNF) in Parkinson's disease, delivered via intermittent bilateral intraputamenal infusions using convection enhanced delivery (CED) ... did not meet the primary efficacy endpoint." The Parkinson's UK position is [2]: "These initial findings appear disappointing but the full results and analysis may yet reveal positive insights." There has been a long history of claim and counter-claim about the efficacy of GDNF, but I think that this puts an end to the chances of GDNF being part of a useful therapy for PD. References: [1] News [2] Parkinson's UK - Update on GDNF trial: analysis underway John
__________________
Born 1955. Diagnosed PD 2005. Meds 2010-Nov 2016: Stalevo(75 mg) x 4, ropinirole xl 16 mg, rasagiline 1 mg Current meds: Stalevo(75 mg) x 5, ropinirole xl 8 mg, rasagiline 1 mg |
||
|
 Reply With Quote
|
| "Thanks for this!" says: |
|
07-11-2016, 06:26 PM
|
#12 | ||
|
|||
|
Member
|
"These initial findings appear disappointing but the full results and analysis may yet reveal positive insights."
There has been a long history of claim and counter-claim about the efficacy of GDNF, but I think that this puts an end to the chances of GDNF being part of a useful therapy for PD. John[/QUOTE] Oh well, as in the immortal words of Queen's John Deacon: "Another one bites the dust" |
||
|
|
Reply With Quote
|
|
07-12-2016, 01:36 PM
|
#13 | ||
|
|||
|
Member
|
 Quote:
__________________
Imad Born in 1943. Diagnosed with PD in 2006. |
||
|
|
Reply With Quote
|
| Reply |
|
|
Similar Threads
|
||||
| Thread | Forum | |||
| Brainsway TMS therapy looks quite promising for PD | Parkinson's Disease | |||
| New Therapy Promising For MS Patients. | Multiple Sclerosis | |||
| GDNF therapy ti begin Phase I trials in PD | Parkinson's Disease | |||
| is it possible to have the GDNF therapy put on the stock market? | Parkinson's Disease | |||
| GDNF Gene Therapy Trial | Parkinson's Disease | |||
Sure!!!!
Linear Mode
