Parkinson's Disease Tulip


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Old 08-24-2016, 02:12 AM #3
jeffreyn jeffreyn is offline
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Join Date: Apr 2016
Location: Australia
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jeffreyn jeffreyn is offline
Member
 
Join Date: Apr 2016
Location: Australia
Posts: 352
8 yr Member
Default Carbidopa correction

Hercules957 said:

"Carbidopa does this . . ."

This is wrong, and I'll correct it for the record. You never know who reads this stuff, seeking to learn from what we write.

Carbidopa doesn't boost AADC, it inhibits AADC. Carbidopa can't cross the blood-brain barrier so it only inhibits AADC outside of the brain, allowing more levodopa to reach the brain.

Carbidopa has no role to play in the topic of this thread, since this thread is about things occurring on the brain side of the blood brain barrier, and Carbidopa can't get there to join the discussion. :-)

On the other hand, Carbidopa has everything to do with the current discussion on the Hinz thread, and I've posted something (hopefully) appropriate over there.
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backpacker11500 (08-26-2016), Bergamotte (08-25-2016), soccertese (08-24-2016)
 

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aadc, brain, dopamine, enzyme, neurons


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