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09-06-2016, 03:32 PM | #1 | ||
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The PREDICT-PD Blog: Short chain fatty acids and gut microbiota differ between patients with Parkinson's disease and age-matched controls
Short chain fatty acids and gut microbiota differ between patients with Parkinson's disease and age-matched controls |
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"Thanks for this!" says: | lab rat (09-08-2016) |
09-06-2016, 03:57 PM | #2 | ||
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"Thanks for this!" says: | eds195 (09-06-2016) |
09-06-2016, 05:16 PM | #3 | ||
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I am onto this possible gut microbiome and Parkinson's link. As a young teen I suffered with severe back acne. The standard treatment back then was to be given high powered broad spectrum antibiotics. I have had gut dysbiosis ever since.. And now I have Parkinson's.. Go figure.
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09-08-2016, 02:29 PM | #4 | ||
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A week ago today I did a fecal Microbiome transplant FMT. Today I've had 2 normal bm's. I think it takes a few days for Microbiome to colonize. I am a believer in Braack hypothesis as the gut is the source of a synuclean. A syn travels the vagus to the central nervous system. Correcting gut bacteria just may be the key to stopping neurological degeneration.
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"Thanks for this!" says: | Bergamotte (04-06-2017), johnt (04-04-2017) |
09-08-2016, 07:01 PM | #5 | ||
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09-09-2016, 08:53 AM | #6 | |||
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In homeopathy school we were taught that suppressing a skin problem can definitey lead to deep chronic pathos. Dr. Perlmutter theorizes that many PWP present with shingles - so the question becomes how to treat the detoxification process of the bodys' attempt to dispel toxin... somehow the word "gently" comes to mind.... Kind regards, MD
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04-04-2017, 02:03 PM | #7 | ||
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A paper [1] by Sampson et al, which is behind a paywall, has some interesting findings.
"Synucleinopathies are characterized by aggregation of the protein α-synuclein (αSyn), often resulting in motor dysfunction as exemplified by Parkinson’s disease (PD). Using mice that overexpress αSyn, we report herein that gut microbiota are required for motor deficits, microglia activation, and αSyn pathology. Antibiotic treatment ameliorates, while microbial re-colonization promotes, pathophysiology in adult animals ... Indeed, oral administration of specific microbial metabolites to germ-free mice promotes neuroinflammation and motor symptoms. Remarkably, colonization of αSyn-overexpressing mice with microbiota from PD-affected patients enhances physical impairments compared to microbiota transplants from healthy human donors." Power to the poo! Blackfeather do you have an update of your faecal transplant experiences? Reference [1] "Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson’s Disease Timothy R. Sampson et al. Cell, Dec 2016 http://www.cell.com/action/showImage...2816%2931590-2 John
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Born 1955. Diagnosed PD 2005. Meds 2010-Nov 2016: Stalevo(75 mg) x 4, ropinirole xl 16 mg, rasagiline 1 mg Current meds: Stalevo(75 mg) x 5, ropinirole xl 8 mg, rasagiline 1 mg |
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"Thanks for this!" says: | kiwi33 (04-12-2017) |
04-04-2017, 03:23 PM | #8 | ||
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