The Melbourne, Australia project has reported further progress:

- All 4 patients in the first cohort have received their 30 million stem cells.
- All 4 patients in the second cohort have received their 50 million stem cells.
- The second patient in the third cohort has now received his/her 70 million stem cells.

Press Releases: International Stem Cell Corporation Doses Tenth Patient in Parkinson's Disease Clinical Trial

"The fourth subject of the third cohort, who was the twelfth and final subject of the phase 1 clinical study, was successfully transplanted with the highest dose of ISC-hpNSC® stem cells."

"Interim results of this study will be presented at the upcoming 2019 American Academy of Neurology 71st Annual Meeting in Philadelphia, PA on May 5th, 2019."

International Stem Cell Corporation Completes Enrollment and Dosing in its Parkinson's Disease Clinical Trial Other OTC:ISCO

This announcement has already been covered in another thread by ashleyk.
International Stem Cell Corporation

I'm covering it here as well to join it up with the many previous posts on this topic.

Some good news is that the results of the Phase 1 trial show safety, and possible efficacy.

Some bad news is that no plans were mentioned for a Phase 2 trial, only that "Patients will continue to be evaluated every six months for another five years in the study’s extension phase."

PNT article:
Parkinson's Stem Cell Therapy Shows Safety, Early Efficacy in Small Trial

Press release:
International Stem Cell Corporation Announces Successful Completion of Its Phase 1 Clinical Trial in Parkinson's Disease

"The quality of life of the patients as measured by the Parkinson's Disease Quality of Life Score-39 (PDQ-39) Summary Index, improved 43% for the second cohort at twelve months post-transplantation. This improved to a 45% better score in cohort 2 at 48 months."

I think there is a typo there, in that "48 months" should probably be "24 months". It really can't be 48 months, since cohort 2 has only been observed for 36 months.

I must admit when I saw this thread title, as a Brit, I read Victorian as, during the reign of Queen Victoria!

Great to see the progress being made as reported in time over a long thread. Thanks for the updates jeffreyn