Parkinson's Disease Tulip


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Old 12-10-2016, 10:39 AM #1
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Default Doctors use deep-brain ultrasound to treat tremors

We have seen this before, but it is very interesting and real.....

Doctors use deep-brain ultrasound therapy to treat tremors - BBC News
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Old 12-10-2016, 02:40 PM #2
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Default Ultrsound and MJFF ...

This looks like the best advance since ldopa, so I must have missed something.

I know MJFF are involved with this approach, testing it for tremor and dyskinesia, can someone, (perhaps from MJFF), summarise where we are with this and is it being targeted as a replacement for DBS ?

Neil.
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Old 12-11-2016, 10:08 AM #3
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Quote:
Originally Posted by aftermathman View Post
This looks like the best advance since ldopa, so I must have missed something.

I know MJFF are involved with this approach, testing it for tremor and dyskinesia, can someone, (perhaps from MJFF), summarise where we are with this and is it being targeted as a replacement for DBS ?

Neil.
Isn't this similar to ablation only using sound instead of a hot probe? I'm not sure the results last long - only a few years. In time, the tremors return and you can't do it again.
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Old 12-11-2016, 11:14 AM #4
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Originally Posted by zanpar321 View Post
Isn't this similar to ablation only using sound instead of a hot probe? I'm not sure the results last long - only a few years. In time, the tremors return and you can't do it again.
Actually, this is the ablation therapy you are thinking of. The high frequency ultrasound is what causes the heat that burns and destroys the targeted brain cells. It's works, it's approved(at least for essential tremor and being tested for PD tremor) and it's also non-invasive. On the other hand, as opposed to DBS, it's non-reversable.

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Old 12-11-2016, 11:51 AM #5
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Something I found even as interesting as the procedure itself is located in the bottom video at the 3:30 mark where he discusses opening up the narrow BBB entrance to allow easier and more efficient targeting. He doesn't say much but it could be an important step for meds and other treatments.

Eric
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Old 12-11-2016, 09:11 PM #6
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Originally Posted by Tupelo3 View Post
Actually, this is the ablation therapy you are thinking of. The high frequency ultrasound is what causes the heat that burns and destroys the targeted brain cells. It's works, it's approved(at least for essential tremor and being tested for PD tremor) and it's also non-invasive. On the other hand, as opposed to DBS, it's non-reversible.
That's what I thought. Too bad it isn't permanent. Seems like a false hope and permanent damage is done. DBS is reversable.
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Old 12-12-2016, 10:17 AM #7
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Default DBS is reversible ...

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Originally Posted by zanpar321 View Post
That's what I thought. Too bad it isn't permanent. Seems like a false hope and permanent damage is done. DBS is reversable.
but I would go for non invasive ultrasound over DBS major surgery with the risks of stroke, bleeding and even death.

Now the tech is a lot more advanced the additional accuracy of destroying only those cells you need to gives ultrasound my vote.

Take care,
Neil.
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Old 12-12-2016, 01:32 PM #8
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but I would go for non invasive ultrasound over DBS major surgery with the risks of stroke, bleeding and even death.

Now the tech is a lot more advanced the additional accuracy of destroying only those cells you need to gives ultrasound my vote.

Take care,
Neil.
Ultrasound sounds great but I don't think the positive effects last but a few years and I don't know if you can have DBS at that point.
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Old 12-12-2016, 04:30 PM #9
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I don't know if it's false hope, permanent damage or only lasts a few years, or if they even know at this point. Maybe a professional reading these threads could shed some light.
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Old 12-12-2016, 07:06 PM #10
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Originally Posted by eds195 View Post
I don't know if it's false hope, permanent damage or only lasts a few years, or if they even know at this point. Maybe a professional reading these threads could shed some light.
My Neurologist tells me that ablation lasts only a couple years before the Parkinson's tremor returns. I suppose he could be wrong. I don't think the ultrasound trials have followed patients for more than a few years. I would love to hear a professional shed some light on this.
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