Parkinson's Disease Tulip


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Old 12-28-2016, 10:55 AM #2
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Quote:
Originally Posted by Tupelo3 View Post
New details learned about a key cellular protein could lead to treatments for neurodegenerative diseases, such as Parkinson's, Huntington's, Alzheimer's, and amyotrophic lateral sclerosis (ALS). In a new study, researchers in the laboratory of Steven Finkbeiner, MD, PhD, at the Gladstone Institutes used a different protein, Nrf2, to restore levels of the disease-causing proteins to a normal, healthy range, thereby preventing cell death.

The researchers tested Nrf2 in two models of Parkinson's disease: cells with mutations in the proteins LRRK2 and α-synuclein. By activating Nrf2, the researchers turned on several "house-cleaning" mechanisms in the cell to remove excess LRRK2 and α-synuclein."Nrf2 coordinates a whole program of gene expression, but we didn't know how important it was for regulating protein levels until now"

Single protein may hold secret to treating Parkinson's disease and more | EurekAlert! Science News
Some Nfr2 activators are DHA, Gastrodin, Sulforaphane from broccoli, Pterostilbene, Curcumin, Green tea, Milk thistle, Bacopa, and Ashwagandha.
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