Parkinson's Disease Tulip

Reply
 
Thread Tools Display Modes
Old 11-13-2013, 11:53 AM #1
johnt johnt is offline
Senior Member
 
Join Date: Apr 2009
Location: Stafford, UK
Posts: 1,035
10 yr Member
johnt johnt is offline
Senior Member
 
Join Date: Apr 2009
Location: Stafford, UK
Posts: 1,035
10 yr Member
Default Do lentils contain levodopa?

Do lentils contain levodopa?

As far as a know the only foods containing levodopa are macuna puriens and fava beans.

On Monday and yesterday I ate large amounts of red split lentils, about 50gm dried weight in total. I found that I was "on" all day with just one dose in the morning of Stalevo, plus the other non-levodopa drugs I take. Put another way, I went without about 250mg of levodopa without effect.

(Note, I'm not saying this was better than my normal drugs, just that it was an alternative way to give the same effect.)

Today, lentil-free I'm back on my normal drug regime.

Googling around I came up with one reference:

"Determination of levodopa by capillary zone electrophoresis using an acidic phosphate buffer and its application in the analysis of beans."

Zhang, Zhai and Hu write:

"A simple capillary zone electrophoresis method has been developed for the quantification of levodopa in broad bean and lentil."

http://openagricola.nal.usda.gov/Record/IND43708486

Unfortunately, I can't get through the pay wall to get to the results, so I can't be sure that the paper above shows that lentils do contain levodopa.

John
__________________
Born 1955. Diagnosed PD 2005.
Meds 2010-Nov 2016: Stalevo(75 mg) x 4, ropinirole xl 16 mg, rasagiline 1 mg
Current meds: Stalevo(75 mg) x 5, ropinirole xl 8 mg, rasagiline 1 mg
johnt is offline   Reply With QuoteReply With Quote
Old 11-13-2013, 01:27 PM #2
soccertese soccertese is offline
Magnate
 
Join Date: Nov 2007
Posts: 2,522
10 yr Member
soccertese soccertese is offline
Magnate
 
Join Date: Nov 2007
Posts: 2,522
10 yr Member
Default

lentils are a staple in my diet and i have never perceived a benefit, they are more likely to interfere with ldopa absorption since they are about 20% protein.

ldopa is actually considered a toxin, something plants developed as a defense to keep animals from eating the plant. if they ever had ldopa, i imagine over the hundreds of years they have been grown it has been selected/bred out.

lentils/pulses are a staple in south asia, i assume billions of people consume them, i can't believe they have ldopa.

as far as electrophoresis in the home, i imagine anything is possible, when i did it in college i think the gel had to be handled/prepared very carefully since it was slightly toxic, a highly regulated power source was used to give consistant results. i used it just to compare banding on different samples of oats to compare/contrast their genetics, not to make specific measurements. you still need to quantify the bands which i imagine needs another instrument to optically measure the density of the band and compare it against a control of pure l-dopa. so measuring very small amounts - if too much won't get bands, just huge smudges, need more than a kitchen scale, filters, centrifuge

have fun.
soccertese is offline   Reply With QuoteReply With Quote
Old 08-17-2019, 07:27 AM #3
Danny80 Danny80 is offline
Newly Joined
 
Join Date: Aug 2019
Posts: 1
Danny80 Danny80 is offline
Newly Joined
 
Join Date: Aug 2019
Posts: 1
Default I am also wondering this

I started eating a lot of pea/rice protein isolate and have been noticing some effect
Danny80 is offline   Reply With QuoteReply With Quote
Old 08-17-2019, 09:52 PM #4
johnt johnt is offline
Senior Member
 
Join Date: Apr 2009
Location: Stafford, UK
Posts: 1,035
10 yr Member
johnt johnt is offline
Senior Member
 
Join Date: Apr 2009
Location: Stafford, UK
Posts: 1,035
10 yr Member
Default

Danny, welcome to the forum.

Almost 6 years later ...

Unfortunately, the link given is broken. But, this one now works:
Get PDF - Determination of levodopa by capillary zone electrophoresis using an acidic phosphate buffer and its application in the analysis of beans
It is still behind a pay wall.

Regarding the determination of levodopa in lentils I would now suggest spectroscopy. There's many "citizen science" articles about the technique.

John
__________________
Born 1955. Diagnosed PD 2005.
Meds 2010-Nov 2016: Stalevo(75 mg) x 4, ropinirole xl 16 mg, rasagiline 1 mg
Current meds: Stalevo(75 mg) x 5, ropinirole xl 8 mg, rasagiline 1 mg
johnt is offline   Reply With QuoteReply With Quote
Reply

Tags
electrophoresis, lentils, levodopa

Thread Tools
Display Modes

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is Off


Similar Threads
Thread Thread Starter Forum Replies Last Post
How much levodopa are you on? Jim091866 Parkinson's Disease 28 08-28-2012 02:12 AM
IM levodopa Jim091866 Parkinson's Disease 1 02-13-2012 08:59 PM
For those of you on levodopa caldeerster Parkinson's Disease 8 06-27-2011 10:50 AM
Drug interactions of Coumadin, Comtan, Carbidopa And Levodopa, Carbidopa And Levodopa lou_lou Parkinson's Disease 0 06-23-2011 11:50 PM
levodopa inconsistencies? lindylanka Parkinson's Disease 1 07-19-2010 09:06 AM


All times are GMT -5. The time now is 03:19 PM.

Powered by vBulletin • Copyright ©2000 - 2020, Jelsoft Enterprises Ltd.
Search Engine Optimisation provided by DragonByte SEO v2.0.31 (Lite) - vBulletin Mods & Addons Copyright © 2020 DragonByte Technologies Ltd.

vBulletin Optimisation provided by vB Optimise v2.7.1 (Lite) - vBulletin Mods & Addons Copyright © 2020 DragonByte Technologies Ltd.
 

NeuroTalk Forums

Helping support those with neurological and related conditions.

 

The material on this site is for informational purposes only,
and is not a substitute for medical advice, diagnosis or treatment
provided by a qualified health care provider.


Always consult your doctor before trying anything you read here.