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Any Updates On MSDC-0160?

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Old 06-16-2017, 01:49 PM   #1
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Default Any Updates On MSDC-0160?

Here is one year and a half old link to this repurposed diabetes that showed promise in treating PD.
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Old 06-17-2017, 02:57 AM   #2
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This December 2016 paper reports some results for MSDC-0160, based of tissue culture, C. elegans and mouse models Mitochondrial pyruvate carrier regulates autophagy, inflammation, and neurodegeneration in experimental models of Parkinson’s disease | Science Translational Medicine.
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Old 08-10-2017, 11:24 AM   #3
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Default CPT Approves Funding for Research Investigation of MSDC-0160

Originally Posted by Blackfeather View Post
Here is one year and a half old link to this repurposed diabetes that showed promise in treating PD.
Diabetes drug slows experimental Parkinson's disease progression, human trials to begin next year -- ScienceDaily
Blackfeather, here is some new information on MSDC-0160. CPT will be funding more research, which will be done at the Van Andel Research Institute.

Cure Parkinson's Trust | CPT Approves Funding for Two Pre-clinical Studies of Anti-diabetic Drugs
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Old 08-10-2017, 02:40 PM   #4
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Thanks Tupe for the update. seems as though there is plethora of diabetes drugs being researched now for treating PD. Another diabetes drug being investigated that I reccently discovered is intranasal insulin. Maybe some of you folks are knowledgable about this one. Novolin R is a type of insulin being invesigated.
It bypasses the blood stream and crosses the BBB where it is taken up by insulin receptors in the brain. Its being investigated for treatment of Asheimer's disease and MSA as well. It's inexpensive and available now.
Treatment of Parkinson Disease and Multiple System Atrophy Using Intranasal Insulin. - Full Text View - ClinicalTrials.gov
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