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06-23-2017, 11:52 PM | #1 | ||
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"Our findings raise the possibility that an immunotherapy approach could be used to increase the immune system's tolerance for alpha-synuclein ..."
NeuroscienceNews article: "Parkinson's is Partly an Autoimmune Disease" Parkinson's is Partly an Autoimmune Disease - Neuroscience News (hat tip to 999---666 at HU for this link) Research paper: "T cells from patients with Parkinson's disease recognize alpha-synuclein peptides", Sulzer, D. et al. Nature (2017), doi:10.1038/nature22815 T cells from patients with Parkinson’s disease recognize α-synuclein peptides : Nature : Nature Research (abstract only, rest is behind the paywall) This research builds on earlier work reported in a 2014 paper, which contains some good background information. Research paper: "MHC-I expression renders catecholaminergic neurons susceptible to T-cell-mediated degeneration", Cebrian, C. et al. Nature Communications 5, 3633 (2014), doi:10.1038/ncomms4633 MHC-I expression renders catecholaminergic neurons susceptible to T-cell-mediated degeneration | Nature Communications (this is an open-access research paper) |
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