Parkinson's Disease Tulip

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Old 04-27-2018, 01:41 AM #1
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Default More evidence of a link between systemic inflammation and Parkinson's disease

"... the incidence of PD was 78% lower in patients with IBD who received anti-TNF therapy compared with those who did not ..."

"These findings support a role of systemic inflammation in the development of both PD and IBD ..."

Medscape article: Old Drug May Get New Life in Parkinson's Prevention.
Medscape: Medscape Access

EurekAlert article: Parkinson's disease among patients with inflammatory bowel disease.
Parkinson's disease among patients with inflammatory bowel disease | EurekAlert! Science News

Research paper (not open access, only "Key Points" and "Abstract" are accessible): Anti-Tumor Necrosis Factor Therapy and Incidence of Parkinson Disease Among Patients With Inflammatory Bowel Disease, Inga Peter et al., JAMA Neurol. Published online April 23, 2018. doi:10.1001/jamaneurol.2018.0605.
Anti–Tumor Necrosis Factor Therapy and Incidence of Parkinson Disease Among Patients With Inflammatory Bowel Disease | Gastroenterology | JAMA Neurology | JAMA Network

Editorial (not open access, only first page is accessible): Discovering New Benefits From Old Drugs With Big Data - Promise for Parkinson Disease, Abby Olsen et al., JAMA Neurol. Published online April 23, 2018. doi:10.1001/jamaneurol.2018.0345.
Discovering New Benefits From Old Drugs With Big Data—Promise for Parkinson Disease | Gastroenterology | JAMA Neurology | JAMA Network

Although the research paper and the editorial are not open access, I found the bits that were accessible to be of interest.
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Old 04-27-2018, 03:12 AM #2
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I've just noticed that the SoPD blog has done a substantial post on this topic.

IBD+TNF AB ≠ PD? | The Science of Parkinson's
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Old 04-28-2018, 05:51 AM #3
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Thanks jeffreyn - interesting and potentially very promising.
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Old 04-28-2018, 06:51 AM #4
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Default More articles

A few other websites have now written articles covering this research paper. I found the following articles to be of interest, particularly as they include expert commentary from independent researchers.

AlzForum article: Treat IBD, Dodge PD? Epidemiology Ties Parkinsonís to Inflammation.
Treat IBD, Dodge PD? Epidemiology Ties Parkinson’s to Inflammation | ALZFORUM

MEDPAGE TODAY article: Anti-TNF Cuts PD Risk in IBD
Anti-TNF Cuts PD Risk in IBD | Medpage Today

MANAGED HEALTH CARE CONNECT article: IBD Patients Treated With Anti-TNF Drugs Have a Lower Risk of Parkinsonís
https://www.managedhealthcareconnect...sk-parkinson-s
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Old 04-29-2018, 12:51 PM #5
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I wonder if IV glutathione would help prevent PD. Also, what about non-steroidal anti-inflammatory drugs like Aleve. I guess I am asking whether any kind of anti-inflammatory would be of interest.
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Old 08-21-2019, 01:21 AM #6
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Default More evidence of a link between IBD and PD

"Corticosteroid and anti-TNF use may prevent PD in patients with IBD."

Patients with Inflammatory Bowel Disease Are at an Increased Risk of Parkinson's Disease: A South Korean Nationwide Population-Based Study (2019):

Patients with Inflammatory Bowel Disease Are at an Increased Risk of Parkinson's Disease: A South Korean Nationwide Population-Based Study. - PubMed - NCBI
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Old 08-22-2019, 09:02 AM #7
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Default Curcumin

If I had Parkinson's, I would be taking 1 gram or more of curcumin.



Emerging Role of Curcumin in Parkinsons Disease | OMICS International


curcumin parkinson's - Google Search
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Old 08-22-2019, 01:43 PM #8
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Default L serine

[QUOTE=ashleyk;1279090]If I had Parkinson's, I would be taking 1 gram or more of curcumin.

has anyone checked out l serine?


that is L serine
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Old 08-22-2019, 01:48 PM #9
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Could This Radical New Approach to Alzheimer’s Lead to a Breakthrough? | Fortune

Could This Radical New Approach to Alzheimer’s Lead to a Breakthrough? | Fortune
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