Go Back   NeuroTalk Support Groups > >

Parkinson's Disease Tulip

More evidence of a link between systemic inflammation and Parkinson's disease

Reply
 
Thread Tools Display Modes
Old 04-27-2018, 01:41 AM   #1
jeffreyn
Member
 
Join Date: Apr 2016
Location: Australia
Posts: 327
Default More evidence of a link between systemic inflammation and Parkinson's disease

"... the incidence of PD was 78% lower in patients with IBD who received anti-TNF therapy compared with those who did not ..."

"These findings support a role of systemic inflammation in the development of both PD and IBD ..."

Medscape article: Old Drug May Get New Life in Parkinson's Prevention.
Medscape: Medscape Access

EurekAlert article: Parkinson's disease among patients with inflammatory bowel disease.
Parkinson's disease among patients with inflammatory bowel disease | EurekAlert! Science News

Research paper (not open access, only "Key Points" and "Abstract" are accessible): Anti-Tumor Necrosis Factor Therapy and Incidence of Parkinson Disease Among Patients With Inflammatory Bowel Disease, Inga Peter et al., JAMA Neurol. Published online April 23, 2018. doi:10.1001/jamaneurol.2018.0605.
Anti–Tumor Necrosis Factor Therapy and Incidence of Parkinson Disease Among Patients With Inflammatory Bowel Disease | Gastroenterology | JAMA Neurology | JAMA Network

Editorial (not open access, only first page is accessible): Discovering New Benefits From Old Drugs With Big Data - Promise for Parkinson Disease, Abby Olsen et al., JAMA Neurol. Published online April 23, 2018. doi:10.1001/jamaneurol.2018.0345.
Discovering New Benefits From Old Drugs With Big Data—Promise for Parkinson Disease | Gastroenterology | JAMA Neurology | JAMA Network

Although the research paper and the editorial are not open access, I found the bits that were accessible to be of interest.
jeffreyn is offline   Reply With Quote
"Thanks for this!" says:
johnt (04-27-2018), kiwi33 (04-28-2018), lab rat (08-29-2019)
Old 04-27-2018, 03:12 AM   #2
jeffreyn
Member
 
Join Date: Apr 2016
Location: Australia
Posts: 327
Default Update

I've just noticed that the SoPD blog has done a substantial post on this topic.

IBD+TNF AB ≠ PD? | The Science of Parkinson's
jeffreyn is offline   Reply With Quote
"Thanks for this!" says:
kiwi33 (04-28-2018)
Old 04-28-2018, 05:51 AM   #3
kiwi33
Magnate
Community Welcome Team
 
kiwi33's Avatar
 
Join Date: Jan 2015
Location: Sydney, Australia.
Posts: 2,621
My Mood: More evidence of a link between systemic inflammation and Parkinson's disease
Default

Thanks jeffreyn - interesting and potentially very promising.
__________________
Knowledge is power.
kiwi33 is offline   Reply With Quote
Old 04-28-2018, 06:51 AM   #4
jeffreyn
Member
 
Join Date: Apr 2016
Location: Australia
Posts: 327
Default More articles

A few other websites have now written articles covering this research paper. I found the following articles to be of interest, particularly as they include expert commentary from independent researchers.

AlzForum article: Treat IBD, Dodge PD? Epidemiology Ties Parkinson’s to Inflammation.
Treat IBD, Dodge PD? Epidemiology Ties Parkinson’s to Inflammation | ALZFORUM

MEDPAGE TODAY article: Anti-TNF Cuts PD Risk in IBD
Anti-TNF Cuts PD Risk in IBD | Medpage Today

MANAGED HEALTH CARE CONNECT article: IBD Patients Treated With Anti-TNF Drugs Have a Lower Risk of Parkinson’s
https://www.managedhealthcareconnect...sk-parkinson-s
jeffreyn is offline   Reply With Quote
Old 04-29-2018, 12:51 PM   #5
KNPV
Junior Member
 
Join Date: Apr 2017
Posts: 86
My Mood: More evidence of a link between systemic inflammation and Parkinson's disease
Default

I wonder if IV glutathione would help prevent PD. Also, what about non-steroidal anti-inflammatory drugs like Aleve. I guess I am asking whether any kind of anti-inflammatory would be of interest.
KNPV is offline   Reply With Quote
Old 08-21-2019, 01:21 AM   #6
jeffreyn
Member
 
Join Date: Apr 2016
Location: Australia
Posts: 327
Default More evidence of a link between IBD and PD

"Corticosteroid and anti-TNF use may prevent PD in patients with IBD."

Patients with Inflammatory Bowel Disease Are at an Increased Risk of Parkinson's Disease: A South Korean Nationwide Population-Based Study (2019):

Patients with Inflammatory Bowel Disease Are at an Increased Risk of Parkinson's Disease: A South Korean Nationwide Population-Based Study. - PubMed - NCBI
jeffreyn is offline   Reply With Quote
"Thanks for this!" says:
johnt (08-21-2019)
Old 08-22-2019, 09:02 AM   #7
ashleyk
Member
 
Join Date: Oct 2006
Location: New England
Posts: 228
Default Curcumin

If I had Parkinson's, I would be taking 1 gram or more of curcumin.



Emerging Role of Curcumin in Parkinsons Disease | OMICS International


curcumin parkinson's - Google Search
ashleyk is offline   Reply With Quote
Old 08-22-2019, 01:43 PM   #8
KNPV
Junior Member
 
Join Date: Apr 2017
Posts: 86
My Mood: More evidence of a link between systemic inflammation and Parkinson's disease
Default L serine

[QUOTE=ashleyk;1279090]If I had Parkinson's, I would be taking 1 gram or more of curcumin.

has anyone checked out l serine?


that is L serine
KNPV is offline   Reply With Quote
Reply

Tags
access, accessible, disease, parkinsons, patients

Thread Tools
Display Modes

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is Off


Similar Threads
Thread Thread Starter Forum Replies Last Post
ALZFORUM article: Genetic Findings Link PD to Crohn's Disease, and to Inflammation jeffreyn Parkinson's Disease 3 01-15-2018 06:41 PM
Even more evidence has linked Parkinson's disease to our gut ... - ScienceAlert NewsBot Parkinson's News 0 03-04-2017 12:51 PM
Inflammation and α-Synuclein’s Prion-like Behavior in Parkinson's Disease—Is There a badboy99 Parkinson's Disease 2 02-14-2014 04:33 PM
More Evidence of Link Between Parkinson's and Pesticides Stitcher Parkinson's Disease 3 02-05-2010 06:10 PM
WOW! Link established between intestinal inflammation and systemic genetic damage lurkingforacure Parkinson's Disease 6 06-10-2009 12:01 AM


All times are GMT -5. The time now is 07:38 PM.
Brought to you by the fine folks who publish mental health and psychology information at Psych CentralMental Health Forums

The material on this site is for informational purposes only, and is not a substitute for medical advice, diagnosis or treatment
provided by a qualified health care provider. Always consult your doctor before trying anything you read here.


Powered by vBulletin • Copyright ©2000 - 2019, Jelsoft Enterprises Ltd.
Search Engine Optimisation provided by DragonByte SEO v2.0.31 (Lite) - vBulletin Mods & Addons Copyright © 2019 DragonByte Technologies Ltd.

vBulletin Optimisation provided by vB Optimise v2.7.1 (Lite) - vBulletin Mods & Addons Copyright © 2019 DragonByte Technologies Ltd.

All posts copyright their original authors • Community GuidelinesTerms of UsePrivacy Policy