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05-04-2018, 12:08 AM | #1 | ||
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... and protects them from degeneration.
Article: Cell Study Provides Hope for Treatment of Parkinson's Disease. Cell Study Provides Hope for Treatment of Parkinson's Disease Research paper (open access): Alpha-synuclein aggregates activate calcium pump SERCA leading to calcium dysregulation. Alpha‐synuclein aggregates activate calcium pump SERCA leading to calcium dysregulation | EMBO Reports The SoPD blog has done a substantial post on this paper. I think this is because this discovery reveals another way by which the elimination/reduction of alpha-synuclein aggregates could be neuroprotective. The blog post includes some information on the alpha-synuclein immunotherapy trials of AFFiRiS and Prothena, and even a few words (in the comments section) on the ongoing CliniCrowd mannitol trial. When SERCA goes berserker | The Science of Parkinson's NB: Like a lot of SoPD posts, this one starts with a largely unrelated preamble. The actual post begins after the line (in bold) "What does this have to do with Parkinson's" |
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