Parkinson's Disease Tulip


advertisement
Reply
 
Thread Tools Display Modes
Old 10-18-2018, 11:58 AM #1
eds195 eds195 is offline
Member
 
Join Date: Feb 2015
Location: NJ
Posts: 153
8 yr Member
eds195 eds195 is offline
Member
 
Join Date: Feb 2015
Location: NJ
Posts: 153
8 yr Member
Default Clinical Improvements From DBS Mostly Meet Parkinson’s Patients’ Expectations

I was encouraged by most of these numbers for improved quality of life.....and thinking the procedure should improve going forward.

Most Parkinson's Patient Expectations Met on DBS Improvements, Study Says
eds195 is offline   Reply With QuoteReply With Quote

advertisement
Old 10-18-2018, 03:35 PM #2
johnt johnt is offline
Senior Member
 
Join Date: Apr 2009
Location: Stafford, UK
Posts: 1,059
15 yr Member
johnt johnt is offline
Senior Member
 
Join Date: Apr 2009
Location: Stafford, UK
Posts: 1,059
15 yr Member
Default

Am I missing something? If I understand the report on the paper correctly, it contains a curious mixture of data.

E.g. "a significant reduction in total levodopa equivalent daily doses (mg/day) of 50.45% was observed in patients treated with STN-DBS". Although, everything else being equal, this is desirable, it is not the same thing as a 50.45% reduction in symptoms.

E.g. "Most patients reported that expectations of improvement after DBS were met, namely 64% for motor symptoms, 71% for quality of life, and 83% for reductions in daily medication dose." I take this to mean that if I went into the procedure with the expectation that, for some measure, I would get an improvement of 10%, say, and I got this, then I could write that 100% of my expectations in that measure had been met.

John
__________________
Born 1955. Diagnosed PD 2005.
Meds 2010-Nov 2016: Stalevo(75 mg) x 4, ropinirole xl 16 mg, rasagiline 1 mg
Current meds: Stalevo(75 mg) x 5, ropinirole xl 8 mg, rasagiline 1 mg
johnt is offline   Reply With QuoteReply With Quote
Old 10-25-2018, 11:32 AM #3
moondaughter's Avatar
moondaughter moondaughter is offline
Member
 
Join Date: Jul 2010
Location: rural Eastern Oregon
Posts: 613
10 yr Member
moondaughter moondaughter is offline
Member
moondaughter's Avatar
 
Join Date: Jul 2010
Location: rural Eastern Oregon
Posts: 613
10 yr Member
Default intake verses uptake?

Quote:
Originally Posted by johnt View Post

Although, everything else being equal, this is desirable, it is not the same thing


John
John,

Is another way of languaging what you are saying here is that intake is not the same thing as amount absorbed? MD
__________________
Smooth seas do not make skillful sailors....
Nature loves courage.


“The day science begins to study non-physical phenomena, it will make more progress in one decade than in all the previous centuries of its existence.”
~ Nikola Tesla
moondaughter is offline   Reply With QuoteReply With Quote
Old 10-25-2018, 11:52 PM #4
johnt johnt is offline
Senior Member
 
Join Date: Apr 2009
Location: Stafford, UK
Posts: 1,059
15 yr Member
johnt johnt is offline
Senior Member
 
Join Date: Apr 2009
Location: Stafford, UK
Posts: 1,059
15 yr Member
Default

moondaugther,

What you say is correct. But that wasn't the point I was trying to make.

Suppose a doctor gives me a drug promising that it would halve my tremor, while not making anything else worse. I take the drug and it does just that. It has done exactly what I was told it would do: it has met 100% of my expectations. But, even if we only consider tremor, it has only met half my need.

Perhaps this is one of the occasions where UK English and US English differ. For instance, in the UK we tell our children to walk on the "pavement"!

John
__________________
Born 1955. Diagnosed PD 2005.
Meds 2010-Nov 2016: Stalevo(75 mg) x 4, ropinirole xl 16 mg, rasagiline 1 mg
Current meds: Stalevo(75 mg) x 5, ropinirole xl 8 mg, rasagiline 1 mg
johnt is offline   Reply With QuoteReply With Quote
Reply

Tags
improved, life, procedure, quality, thinking


Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is Off


Similar Threads
Thread Thread Starter Forum Replies Last Post
Voyager’s Gene Therapy Improves Parkinson’s Patients’ Movement Over Long Term eds195 Parkinson's Disease 8 03-29-2018 05:53 AM
MRI-Focused Ultrasound Undergoing Phase 3 Clinical Trial for Parkinson’s Treatment eds195 Parkinson's Disease 3 03-18-2018 10:46 AM


All times are GMT -5. The time now is 01:09 PM.

Powered by vBulletin • Copyright ©2000 - 2024, Jelsoft Enterprises Ltd.

vBulletin Optimisation provided by vB Optimise v2.7.1 (Lite) - vBulletin Mods & Addons Copyright © 2024 DragonByte Technologies Ltd.
 

NeuroTalk Forums

Helping support those with neurological and related conditions.

 

The material on this site is for informational purposes only,
and is not a substitute for medical advice, diagnosis or treatment
provided by a qualified health care provider.


Always consult your doctor before trying anything you read here.