In early PD, can changes to L-dopa dosage take 2 weeks to take full effect?

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09-22-2019, 12:09 PM

wriga

Junior Member

Join Date: Mar 2019

Location: Grenoble, France

Posts: 12

wriga

Junior Member

Join Date: Mar 2019

Location: Grenoble, France

Posts: 12

I remember reading an article some time ago about storage of levodopa in muscle tissue of pigs. Of course I can't find it now, but I did find this one on rats. It appears that levodopa is not rapidly decarboxylated in muscle so has a longer half life than in blood.

The effect of carbidopa on plasma and muscle levels of L-dopa, dopamine, and their metabolites following L-dopa administration to rats. - PubMed - NCBI

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jeffreyn (09-22-2019)

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dopamine, effects, found, response, weeks

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In early PD, can changes to L-dopa dosage take 2 weeks to take full effect?

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