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Results out on the NILO-PD trial of Nilotinib

 
 
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Old 12-05-2019, 07:40 PM #1
Tupelo3 Tupelo3 is offline
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Join Date: Mar 2013
Location: New Jersey
Posts: 832
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Tupelo3 Tupelo3 is offline
Member
 
Join Date: Mar 2013
Location: New Jersey
Posts: 832
10 yr Member
Default Results out on the NILO-PD trial of Nilotinib
Results of the NILO-PD (Northwestern University) phase 2 trial of Nilotinib show the drug to be safe & tolerable. Unfortunately, it did not demonstrate any benefit for Parkinson's symptoms or biological measures. Basically, it doesn't have very good BBB penetration. Trials will begin on several other c-Abl inhibitors which appear to have better brain penetration.

There will be a webinar on Dec. 17th where more detail will be provided and questions answered.

Though safe, nilotinib does not show promise for benefit for Parkinson's disease
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"Thanks for this!" says:
anagirl (12-12-2019), jeffreyn (12-06-2019), johnt (12-06-2019), olsen (12-06-2019), soccertese (12-06-2019), TheDub1 (12-26-2019)
 

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nilo-pd, nilotinib, penetration, results, trial

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