Parkinson's Disease Tulip


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Old 12-18-2021, 10:27 PM #6
jeffreyn jeffreyn is offline
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jeffreyn jeffreyn is offline
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Join Date: Apr 2016
Location: Australia
Posts: 352
8 yr Member
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"The failure of Nilotinib to provide a clinically meaningful benefit in PD patients in two double-blind studies is discouraging, but may be explained by the fact that nilotinib does not accumulate in the brain at concentrations sufficient to inhibit c-Abl."

https://movementdisorders.onlinelibr...1002/mds.28858
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