Well, at this point I feel like just giving up. It isn't because you all haven't been encouraging. I guess it's because I'm confused by all of the complexity. I said at the beginning of this thread that I don't want to be diagnosed with PD, but I sure would like to know what's happening to me, and I sure would like to be able to set a course.

My GP has delegated all of my meds to a person who is credentialed as a psychologist and a nurse practitioner. He wants me to take cymbalta starting tomorrow. He didn't even want to listen to my symptoms. He just brought out three boxes of samples: 30mg for one week and then 60mg after that.

Maybe this will help me from feeling so fatigued. Every day, about mid-day, I get so tired I feel like I'm ready for death. I've tried coffee, but even just one cup makes my sleep problems much worse.

Anyway, I didn't get any instructions about when would be the best time of day to take cymbalta. Does anyone have any suggestions?

Karl

the reason i mentioned benedryl is because it works the way artane does. on the other side of the dopamine equation. they use it in er for epileptics in seizure. benedryl works well for many atypicals.. like myself. one of my first symptoms was depression. not that benedryl works for depression, but my internal specialist and psychiatrist are working towards trying to figure out what all is off kilter and if benedryl works for me.. why? for me it works in relaxation of muscles and slows my breathing.

here is a fascinating link about dopamine.

http://bprayer0.tripod.com/bprayer/dopamine.html

I wasn't told any particular time to take it, either, but doc said take it with food because it's hard on the stomach. If it affects your sleep, shift the time accordingly, I've been told.

It may help you with the tiredness because it fosters a longer cycle of both serotonin and norepinephrine (two neurotransmitter chemicals) that affect well-being and energy, respectively. I'll leave it at that for now.

Do you know how to do a private message (PM) on this forum? You are welcome to call on me if there's anything I didn't make clear, or just for suppport.

It WILL get less burdensome. The sun is still shining out there somewhere.

Jaye