genetics: miRNAs in Neurodegeneration

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08-31-2007, 12:23 PM

RLSmi

Member

Join Date: Oct 2006

Location: dx'd4/01@63 Louisiana

Posts: 562

RLSmi

Member

Join Date: Oct 2006

Location: dx'd4/01@63 Louisiana

Posts: 562

Thanks for this, Madelyn. You are "quick on the draw". I subscribe to Science but have not yet picked up this week's issue.
miRNAs are the natural, endogenous counterparts of siRNAs that can be custom-made synthetically and used to suppress the expression of almost any gene. My collaborator in research and I are doing just that in cultured human fibroblasts to determine the effects of the extracellular matrix proteins collagen and fibronectin on one another.
Robert

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