Parkinson's Disease Tulip


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Old 11-16-2007, 08:41 PM #11
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Default Yes I wonder about ...

that as well.

Wouldn't it be great to "talk" to someone with first hand experience of this.

Neil.
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Old 11-16-2007, 11:26 PM #12
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Default

Quote:
Originally Posted by aftermathman View Post

Wouldn't it be great to "talk" to someone with first hand experience of this.

Neil.

Yes it would be nice to talk to one of these people in person. I'm just afraid they would say... yes, my PD is cured but now I have lead poisoning.

GregD
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Old 11-17-2007, 06:53 AM #13
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Default worth trying ?

I sent follwing message via their website form:
we are members of neurotalk forum
http://neurotalk.psychcentral.com/fo...aysprune=&f=34
we wish to have e-mail contacts of one of Parkinson patients treated by you so he may give testimony to the forum/ thank you
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Old 11-17-2007, 09:12 AM #14
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Default service@stemcellschina.com : reply

Just got this e-mail
Patient Services <service@stemcellschina.com> to me, kotan
show details 2:31 pm (1˝ hours ago)

Dear I Mark,
Thank you for the opportunity. Kotan who works with Tiantan hospital will
follow up with you. I have cc'ed her here. I think the best person is going
to be the first foreign patient that was treated who is Penny Thomas as she
is quite communicative. However, Kotan will be able to tell you best.

Thank you.

- Jon
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Old 11-17-2007, 11:34 AM #15
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www.technologyreview.com/Biotech/19645/
How i am understand that, stem cell don't create new cell of diseased part of brain and only support leftover cells of brain.

I hope that's we only on beginng of finding...
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Old 11-17-2007, 11:44 AM #16
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Default Penny Thomas-successfull stem cell implant recipient

Tiantan - Penny Thomas
Wednesday, 19 July 2006

P A T I E N T E X P E R I E N C E – P A R K I N S O N ‘ S

NAME: Penny Thomas

COUNTRY: U.S.A. (Hawaii)

AGE: 52

DIAGNOSIS: Parkinson’s Syndrome (Diagnosed in 2002)

REASON FOR COMING FOR TREATMENT: Penny had Parkinson’s symptoms for eight years.

TREATMENT: Injection into the brain of retinal neural stem cells with a daily cocktail treatment of neurotropic factors.

BEFORE THE TREATMENT (May 11, 2006): Penny had uncontrollable shaking. She had high muscle tension and she looked like she was extremely strong but in fact her muscles were weak. When she was walking or doing anything, she would have freeze ups where she would stop and not be able to continue her motion. If she were talking on the telephone, it would be hard to talk. She could not read or write because of the tremors. She could not eat by herself. She could not get up out of a chair by herself. She could not brush her hair. She could not get out of the bed by herself. She had trouble turning her neck.

See Video (5/13): Before



AFTER THE TREATMENT (July 4, 2006):

See Videos: After1, After2, After3 , After4 , After5

Penny’s shaking was greatly reduced but it still came back from time-to-time. She said that after the treatment at the times that the shaking did come back, if she concentrated, she could stop it. The muscle tension had disappeared. Her strength increased. The freeze ups stopped. She could read and write again, speak on the telephone, and eat by herself. She could get out of a chair and out of bed by herself. Her neck could turn normally and she could brush her hair.

July 21st: (From an e-mail from Penny) - I have returned home safely. I am driving once again after passing my driver's exam. In October I gave up my driving because I did not feel I was safe anymore and it was just adding too much stress to my life. Friends are amazed at what they see they just keep staring at me...my self confidence has returned also. I went sailing the other day... I actually was at the helm of the boat for 2 and 1/2 hours! I feel like I'm a kid again.

October 25th: (From an e-mail from Penny) - Aloha, I have recently returned from traveling for a month on the US mainland visiting friends and relatives. I even attended my 35 year high school class reunion! My how time does change us all and flies by.

I continue to be in a state of great excitement and joy for life. I use to ride horses quite regularly in Colorado, so my friends made sure that I had that experience as well during my visit. I was in heaven!

I saw my 15 year old daughter after not seeing her for 3 months. The first thing she said was "Mom, is that you? You're so strong!"

I am still swimming with the dolphins in the ocean when they choose to come to swim with me!

I am hoping to be able to start to make some reductions of the medications to see how the stem cells will respond soon. I have noticed that I have been missing some of my 10pm meds (because I fall asleep reading) and so am noticing my body seems to be okay with this.

I have also discovered a more natural way to feed the brain L-dopa by an herb known as Macuna puriens. There is a website that has a neuro-program, that my doctor is going to help me be monitored and involved with. It will actually help the stem cells I believe to produce the dopamine.

You might want to check out the websites that I have looked at, they are, www.CHKNutrition.com and www.neuroassist.com. I know there are urinalysis every week or two to determine the dopamine levels in the beginning. I think this is a very important step for people to be able to take in order to step away from prescription meds if they can. I tried a sample instead of Sinemet one afternoon, it seemed to work fine in its place, but of course, that was only once.

January 17th, 2007 (from an E-mail): I just returned from spending five weeks in beautiful snowy Colorado where I was hiking (before the snows came) and cross country skiing (after the snows came) at an elevation of 8000 feet. My body adjusted to the elevation and my strength improved even more. My family said that I looked even better than I did the last time they saw me in October, that I was more relaxed. I believe that was because I knew I could stay longer and was there to relax and spend time healing my body even more in the healing hot springs of the area. I am now back in Hawaii and once again swimming in the ocean. I did notice a shift in my energy level when I first arrived home. My medication and amino acid schedule had shifted so, I believe it was due to the time difference and now that I have been home for 5 days I feel back to normal.

See Video: About the Facilities


Last Updated ( Friday, 29 June 2007 )
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Old 11-17-2007, 01:02 PM #17
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Default Now there is a person after my own heart!

Proactive! Took action! Who says apathy has to win!

Quote:
Originally Posted by imark3000 View Post
I sent follwing message via their website form:
we are members of neurotalk forum
http://neurotalk.psychcentral.com/fo...aysprune=&f=34
we wish to have e-mail contacts of one of Parkinson patients treated by you so he may give testimony to the forum/ thank you
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Born in 1953, 1st symptoms and misdiagnosed as essential tremor in 1992. Dx with PD in 2000.
Currently (2011) taking 200/50 Sinemet CR 8 times a day + 10/100 Sinemet 3 times a day. Functional 90% of waking day but fragile. Failure at exercise but still trying. Constantly experimenting. Beta blocker and ACE inhibitor at present. Currently (01/2013) taking ldopa/carbadopa 200/50 CR six times a day + 10/100 form 3 times daily. Functional 90% of day. Update 04/2013: L/C 200/50 8x; Beta Blocker; ACE Inhib; Ginger; Turmeric; Creatine; Magnesium; Potassium. Doing well.
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Old 11-18-2007, 02:28 AM #18
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Default Good or bad news??

This article appeared on the front page of the Daily Telegraph newspaper in the UK yesterday.

Is it good news (ie, getting round the political problem of using embryos for stem cell research and thereby stopping US goverment funding).

Or bad news (are we back to square one, eg. the 5 year dream is gone!).


http://www.telegraph.co.uk/earth/mai...cidolly116.xml


Dolly creator Prof Ian Wilmut shuns cloning
By Roger Highfield, Science Editor
Last Updated: 6:30pm GMT 16/11/2007Page 1 of 3


The scientist who created Dolly the sheep, a breakthrough that provoked headlines around the world a decade ago, is to abandon the cloning technique he pioneered to create her.

The life and death of Dolly the diva, by Ian Wilmut
Ian Wilmut: The status of the human embryo
Have you say: Can cloning ever be ethical?
Prof Ian Wilmut's decision to turn his back on "therapeutic cloning", just days after US researchers announced a breakthrough in the cloning of primates, will send shockwaves through the scientific establishment.


Ian Wilmut, the creator of Dolly the Sheep
He and his team made headlines around the world in 1997 when they unveiled Dolly, born July of the year before.

But now he has decided not to pursue a licence to clone human embryos, which he was awarded just two years ago, as part of a drive to find new treatments for the devastating degenerative condition, Motor Neuron disease.

Prof Wilmut, who works at Edinburgh University, believes a rival method pioneered in Japan has better potential for making human embryonic cells which can be used to grow a patient's own cells and tissues for a vast range of treatments, from treating strokes to heart attacks and Parkinson's, and will be less controversial than the Dolly method, known as "nuclear transfer."

His announcement could mark the beginning of the end for therapeutic cloning, on which tens of millions of pounds have been spent worldwide over the past decade. "I decided a few weeks ago not to pursue nuclear transfer," Prof Wilmut said.

Most of his motivation is practical but he admits the Japanese approach is also "easier to accept socially."

His inspiration comes from the research by Prof Shinya Yamanaka at Kyoto University, which suggests a way to create human embryo stem cells without the need for human eggs, which are in extremely short supply, and without the need to create and destroy human cloned embryos, which is bitterly opposed by the pro life movement.

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Prof Yamanaka has shown in mice how to turn skin cells into what look like versatile stem cells potentially capable of overcoming the effects of disease.

This pioneering work to revert adult cells to an embryonic state has been reproduced by a team in America and Prof Yamanaka is, according to one British stem cell scientist, thought to have achieved the same feat in human cells.

This work has profound significance because it suggests that after a heart attack, for example, skin cells from a patient might one day be manipulated by adding a cocktail of small molecules to form muscle cells to repair damage to the heart, or brain cells to repair the effects of Parkinson's. Because they are the patient's own cells, they would not be rejected.

In theory, these reprogrammed cells could be converted into any of the 200 other type in the body, even the collections of different cell types that make up tissues and, in the very long term, organs too. Prof Wilmut said it was "extremely exciting and astonishing" and that he now plans to do research in this area.

This approach, he says, represents, the future for stem cell research, rather than the nuclear transfer method that his large team used more than a decade ago at the Roslin Institute, near Edinburgh, to create Dolly.

In this method, the DNA contents of an adult cell are put into an emptied egg and stimulated with a shock of electricity to develop into a cloned embryo, which must be then dismantled to yield the flexible stem cells.

More than a decade ago, biologists though the mechanisms that picked the relevant DNA code that made a cell adopt the identity of skin, rather than muscle, brain or whatever, were so complex and so rigidly fixed that it would not be possible to undo them.

They were amazed when this deeply-held conviction was overturned by Dolly, the first mammal to be cloned from an adult cell, a feat with numerous practical applications, most remarkably in stem cell science.

But although "therapeutic cloning" offers a way to get a patient's own embryonic stem cells to generate unlimited supplies of cells and tissue there is an intense search for alternatives because of pressure from the pro-life lobby, the opposition of President George W Bush and ever present concerns about cloning babies.

Chris
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Old 11-19-2007, 05:16 PM #19
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Thumbs up Five weeks

to xmas, five years to the cure. All is looking good as we hear of some success already from stem cell therapy, with one woman claiming significant improvement in her condition after she undertook stem cell therapy in Asia, although the jury is still out on that one. We hear only this week that successful cloning of blastocyst cells from monkeys is a "Giant Leap" and it can only get better from here on in.

OK, Proffessor Wilmut has declined further research on Blastocyst cloning. but others have moved beyond that. Gene Therapies are in clinical trials. Andy Grove is here to hurry the NIH along with his business model on how to get research into clinical trials with his "Cultural Revolution" format.

Five years.... it could be far less with soooo much happening as we speak.

GO HARD>>>>>> SCIENCE
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Old 11-19-2007, 07:17 PM #20
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no - i'll take this to my own bloviation thread... hop over there if you care to read it.
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