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08-02-2008, 06:55 AM | #1 | |||
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In Remembrance
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Eat Your Orange Peel! Everyone knows that citrus fruits -- oranges, lemons, and grapefruits -- are a healthy food. Packed with vitamin C and bioflavonoids, citrus fruits are to many of us the fresh, sunny taste of good health. But while many people may enjoy the flesh of oranges as a regular part of their healthy diet, few of us eat the intensely-flavored peels of these fruits. That might turn out to be a major error in judgement. New research suggests that we may have been throwing away the best part of the fruit! For some years now, scientists have been quietly investigating limonene, the major component of the essential oil in orange peels, as a potential anti-cancer nutrient.1 In animal models, limonene powerfully prevents tumors of the breast, liver, stomach, skin, and lung, whether given before exposure to a cancer-causing agent, or even after the first cancerous cells have formed. Partly, limonene seems to work by enhancing the body’s phase II detoxification enzymes, which make cancer-causing chemicals more readily excreted by the body in the urine or bile; as well, limonene appears to induce programmed cell suicide (apoptosis) and to block a step (isoprenylation) required for the proteins made by cancer genes (oncogenes) to wreak their havoc. Most excitingly, limonene appears to somehow induce “redifferentiation,” forcing rogue cancer cells to settle down and return to their normal functions in the body. Studies are under way to see if limonene can be used by people with cancer. Citicoline Heals Brain Damage: Cytidine diphosphate choline, or Citicoline for short, is an orthomolecule with a vital job to play in manufacturing the brain’s phospholipids (like phosphatidylserine [PS] and phosphatidylcholine [PC]). In a recent article (see “PS: Remember Your Citicoline!” in The Holistic Lifestyle 1[5]), we reviewed some of the evidence that Citicoline provides powerful nutritional support in many serious disorders of the brain, as well as in the loss of memory associated with “normal” aging. Much of the research on Citicoline has focussed on its ability to help restore healthy brain function after a stroke. Animal studies4 show that Citicoline reduces the size of the brain injury which results when an experimental stroke cuts off the brain’s oxygen supply. The question is, how? Experiments on animals5.6 have suggested that Citicoline has both preventative and regenerative effects on the brain injuries which follow a stroke. On the one hand, strokes usually force brain cells to release some of the fatty acids out of their membranes, a process which can increase the damage inflicted on neurons by free radicals. Animal studies have shown that Citicoline reduces this release of free fatty acids, preventing excess free radical damage during a stroke. http://www.aor.ca/int/magazines/pdf/...range_Peel.pdf
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with much love, lou_lou . . by . , on Flickr pd documentary - part 2 and 3 . . Resolve to be tender with the young, compassionate with the aged, sympathetic with the striving, and tolerant with the weak and the wrong. Sometime in your life you will have been all of these. |
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08-02-2008, 09:37 AM | #2 | |||
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In Remembrance
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I would point out that our own Ron Hutton has taken citicholine (aka CDPcholine) for years and has held up quite well.
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Born in 1953, 1st symptoms and misdiagnosed as essential tremor in 1992. Dx with PD in 2000. Currently (2011) taking 200/50 Sinemet CR 8 times a day + 10/100 Sinemet 3 times a day. Functional 90% of waking day but fragile. Failure at exercise but still trying. Constantly experimenting. Beta blocker and ACE inhibitor at present. Currently (01/2013) taking ldopa/carbadopa 200/50 CR six times a day + 10/100 form 3 times daily. Functional 90% of day. Update 04/2013: L/C 200/50 8x; Beta Blocker; ACE Inhib; Ginger; Turmeric; Creatine; Magnesium; Potassium. Doing well. |
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"Thanks for this!" says: | lou_lou (08-02-2008) |
08-03-2008, 11:31 AM | #3 | |||
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In Remembrance
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Thanks Rick, Yes I have taken CDP choline or citicoline as it is sometimes called, for about 6 years now, in combination with curcumin. I take one 250mg of citicoline per day, with one or 2 curcumin capsules 500mg each.I buy both from iHerb.
I do credit it with slowing down my progression. I have had PD for 17 years now, and I am doing well, but I have been accused of boasting about it. However, I am only trying to pass the message on to help others, and cheer up newly diagnosed with the message that life does not need to stop when you suffer from PD. Last year, I coped with a total of 40 hours in a plane going to Tahiti for 2 weeks holiday. On the boat holiday, I managed one day on one 50mg Sinemet tablet, but other days were poor.and I needed a max of 300mg. Still not bad for 17 years since diagnosis, although I am continuing to deteriorate, but slowly. Over last year, I fell a couple of times and permanently damaged my shoulder. Best wishes to all Ron
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Diagnosed Nov 1991. Born 1936 |
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08-03-2008, 02:07 PM | #4 | |||
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In Remembrance
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Just kidding, but I do think it good to point out some things that Ron might not want to lest he seem a braggart. But these are very important for the archive because we have a limited number of longtime warriors and scientifically trained ones at that. In short, Ron is one of our more valuable "rats", and, while I count him a friend, it is his value as a longterm experiment I am speaking of here.
First, he has held up rather well for a long time. Either he is one of the lucky minority (not likely) or something he has been doing has made a difference. Curcumin and citicholine are prime candidates. Second, he has held up under some real tests. "Stress tested." His bout with the bad tooth was the most recent. Then there was the swan dive through the plate glass of his greenhouse. Struggles with medication changes. His load of PD challenges has been as great as most. Yet, he keeps on ticking. And in doing so he shows that there is hope and that these things we come up with to test do have potential. He is a valuable white rat. Quote:
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Born in 1953, 1st symptoms and misdiagnosed as essential tremor in 1992. Dx with PD in 2000. Currently (2011) taking 200/50 Sinemet CR 8 times a day + 10/100 Sinemet 3 times a day. Functional 90% of waking day but fragile. Failure at exercise but still trying. Constantly experimenting. Beta blocker and ACE inhibitor at present. Currently (01/2013) taking ldopa/carbadopa 200/50 CR six times a day + 10/100 form 3 times daily. Functional 90% of day. Update 04/2013: L/C 200/50 8x; Beta Blocker; ACE Inhib; Ginger; Turmeric; Creatine; Magnesium; Potassium. Doing well. |
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08-03-2008, 03:39 PM | #5 | ||
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Senior Member
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That is so great, and you, Rick, sound as if you are holding up pretty well yourself, so something you all are doing is working. We can see what all Rick takes from his posts (see the bottom list), but would Ron please be willing to share what all he takes? Everyone is different, yes, and nothing is to be construed as medical advice, yes, etc., etc., but it would really help so everyone can compare.
I find it interesting that Ron takes dextromorphan, yet Rick does not (did I get this right?) But both seem to be holding up very well. Thoughts about this? |
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08-03-2008, 04:29 PM | #6 | |||
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In Remembrance
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My signature line is a little misleading. It is not that I am always taking all those, though at times I am. But when I am actively testing something new I often put some or all of the others aside temporarily. For example, right now I am testing mucuna and also taking Acetyl-L-carnitine and alpha lipoic acid and a multi and ginseng. But all the ones I list I have evaluated and tested and consider them to be a part of my regimen. Between tests I try to take them all but one grows sick of pills. I find that I do best if I have my list to keep track of what is proven to me and take as many as I can without stressing about it.
As to the dex, it is on my someday list but I am what they call a "slow metabolizer" for it (a little goes a long way) and I just don't want to add to my liver's burden.
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Born in 1953, 1st symptoms and misdiagnosed as essential tremor in 1992. Dx with PD in 2000. Currently (2011) taking 200/50 Sinemet CR 8 times a day + 10/100 Sinemet 3 times a day. Functional 90% of waking day but fragile. Failure at exercise but still trying. Constantly experimenting. Beta blocker and ACE inhibitor at present. Currently (01/2013) taking ldopa/carbadopa 200/50 CR six times a day + 10/100 form 3 times daily. Functional 90% of day. Update 04/2013: L/C 200/50 8x; Beta Blocker; ACE Inhib; Ginger; Turmeric; Creatine; Magnesium; Potassium. Doing well. |
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08-04-2008, 12:56 AM | #7 | |||
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In Remembrance
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Quote, "would Ron please be willing to share what all he takes?"
Yes of course, I take the following Curcumin one to two 500mg citicoline 250mg acetyl L carnitine 750mg alpha lipoic acid 300mg Since infections can have such a devastating effect, I also take a garlic capsule 1000mg and a spoon of Manuka honey. Rick, thanks for your kind words. Ron
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Diagnosed Nov 1991. Born 1936 |
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"Thanks for this!" says: | lou_lou (08-04-2008) |
08-04-2008, 07:27 AM | #8 | ||
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Senior Member
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Many, many thanks for sharing, so glad you are doing so well at 16 years!.
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"Thanks for this!" says: | lou_lou (08-04-2008) |
08-04-2008, 09:30 AM | #9 | |||
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In Remembrance
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Quote:
citizens? I was 30 -way back then...
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with much love, lou_lou . . by . , on Flickr pd documentary - part 2 and 3 . . Resolve to be tender with the young, compassionate with the aged, sympathetic with the striving, and tolerant with the weak and the wrong. Sometime in your life you will have been all of these. |
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08-04-2008, 10:49 AM | #10 | ||
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Senior Member
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I didn't know that, that is also a long time (our neuro told us 8-12 years, wheelchair around the 5th year, and then a slow decline, his exact words were "it's usually the pnuemonia that'll get ya", so comforting, those doctors), so it's great to hear that so many are doing so well so far out. And the thing I have noticed about all of that group, including yourself, pretty much without exception: all of you are doing alternative things, none have stuck strictly with the traditional Rx drugs. Those that have....sadly, I do not see that they are still around. Unless I am missing something? That speaks volumes to me.
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