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Old 08-02-2008, 06:55 AM #1
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Lightbulb Citocline Heals brain Damage~ eat your orange peels!




Eat Your Orange Peel!

Everyone knows that citrus fruits -- oranges,
lemons, and grapefruits -- are a healthy food.
Packed with vitamin C and bioflavonoids,
citrus fruits are to many of us the fresh,
sunny taste of good health. But while many
people may enjoy the flesh of oranges as a
regular part of their healthy diet, few of us
eat the intensely-flavored peels of these fruits.
That might turn out to be a major error in
judgement. New research suggests that we
may have been throwing away the best part
of the fruit!

For some years now, scientists have been
quietly investigating limonene, the major
component of the essential oil in orange
peels, as a potential anti-cancer nutrient.1 In
animal models, limonene powerfully
prevents tumors of the breast, liver,
stomach, skin, and lung, whether given
before exposure to a cancer-causing agent, or
even after the first cancerous cells have
formed.

Partly, limonene seems to work by
enhancing the body’s phase II
detoxification enzymes, which make
cancer-causing chemicals more readily
excreted by the body in the urine or bile; as
well, limonene appears to induce
programmed cell suicide (apoptosis) and
to block a step (isoprenylation) required for
the proteins made by cancer genes
(oncogenes) to wreak their havoc. Most
excitingly, limonene appears to somehow
induce “redifferentiation,” forcing rogue
cancer cells to settle down and return to their
normal functions in the body.

Studies are under way to
see if limonene can be
used by people with
cancer.

Citicoline Heals Brain Damage:

Cytidine diphosphate choline, or Citicoline
for short, is an orthomolecule with a vital job
to play in manufacturing the brain’s
phospholipids (like phosphatidylserine
[PS] and phosphatidylcholine [PC]). In a
recent article (see “PS: Remember Your
Citicoline!” in The Holistic Lifestyle 1[5]), we
reviewed some of the evidence that
Citicoline provides powerful nutritional
support in many serious disorders of the
brain, as well as in the loss of memory
associated with “normal” aging.

Much of the research on Citicoline has
focussed on its ability to help restore healthy
brain function after a stroke. Animal studies4
show that Citicoline reduces the size of
the brain injury which results when an
experimental stroke cuts off the brain’s
oxygen supply. The question is, how?
Experiments on animals5.6 have suggested
that Citicoline has both preventative and
regenerative effects on the brain injuries which
follow a stroke. On the one hand, strokes
usually force brain cells to release some of
the fatty acids out of their membranes, a
process which can increase the damage
inflicted on neurons by free radicals. Animal
studies have shown that Citicoline reduces
this release of free fatty acids, preventing
excess free radical damage during a
stroke.
PDF
http://www.aor.ca/int/magazines/pdf/...range_Peel.pdf
__________________
with much love,
lou_lou


.


.
by
.
, on Flickr
pd documentary - part 2 and 3

.


.


Resolve to be tender with the young, compassionate with the aged, sympathetic with the striving, and tolerant with the weak and the wrong. Sometime in your life you will have been all of these.
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Old 08-02-2008, 09:37 AM #2
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Default

I would point out that our own Ron Hutton has taken citicholine (aka CDPcholine) for years and has held up quite well.
__________________
Born in 1953, 1st symptoms and misdiagnosed as essential tremor in 1992. Dx with PD in 2000.
Currently (2011) taking 200/50 Sinemet CR 8 times a day + 10/100 Sinemet 3 times a day. Functional 90% of waking day but fragile. Failure at exercise but still trying. Constantly experimenting. Beta blocker and ACE inhibitor at present. Currently (01/2013) taking ldopa/carbadopa 200/50 CR six times a day + 10/100 form 3 times daily. Functional 90% of day. Update 04/2013: L/C 200/50 8x; Beta Blocker; ACE Inhib; Ginger; Turmeric; Creatine; Magnesium; Potassium. Doing well.
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Old 08-03-2008, 11:31 AM #3
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Default Citicoline

Thanks Rick, Yes I have taken CDP choline or citicoline as it is sometimes called, for about 6 years now, in combination with curcumin. I take one 250mg of citicoline per day, with one or 2 curcumin capsules 500mg each.I buy both from iHerb.
I do credit it with slowing down my progression. I have had PD for 17 years now, and I am doing well, but I have been accused of boasting about it. However, I am only trying to pass the message on to help others, and cheer up newly diagnosed with the message that life does not need to stop when you suffer from PD. Last year, I coped with a total of 40 hours in a plane going to Tahiti for 2 weeks holiday.
On the boat holiday, I managed one day on one 50mg Sinemet tablet, but other days were poor.and I needed a max of 300mg. Still not bad for 17 years since diagnosis, although I am continuing to deteriorate, but slowly.
Over last year, I fell a couple of times and permanently damaged my shoulder.
Best wishes to all
Ron
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Old 08-03-2008, 02:07 PM #4
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Default a little bit modest

Just kidding, but I do think it good to point out some things that Ron might not want to lest he seem a braggart. But these are very important for the archive because we have a limited number of longtime warriors and scientifically trained ones at that. In short, Ron is one of our more valuable "rats", and, while I count him a friend, it is his value as a longterm experiment I am speaking of here.

First, he has held up rather well for a long time. Either he is one of the lucky minority (not likely) or something he has been doing has made a difference. Curcumin and citicholine are prime candidates.

Second, he has held up under some real tests. "Stress tested." His bout with the bad tooth was the most recent. Then there was the swan dive through the plate glass of his greenhouse. Struggles with medication changes. His load of PD challenges has been as great as most.

Yet, he keeps on ticking. And in doing so he shows that there is hope and that these things we come up with to test do have potential. He is a valuable white rat.

Quote:
Originally Posted by Ronhutton View Post
Thanks Rick, Yes I have taken CDP choline or citicoline as it is sometimes called, for about 6 years now, in combination with curcumin. I take one 250mg of citicoline per day, with one or 2 curcumin capsules 500mg each.I buy both from iHerb.
I do credit it with slowing down my progression. I have had PD for 17 years now, and I am doing well, but I have been accused of boasting about it. However, I am only trying to pass the message on to help others, and cheer up newly diagnosed with the message that life does not need to stop when you suffer from PD. Last year, I coped with a total of 40 hours in a plane going to Tahiti for 2 weeks holiday.
On the boat holiday, I managed one day on one 50mg Sinemet tablet, but other days were poor.and I needed a max of 300mg. Still not bad for 17 years since diagnosis, although I am continuing to deteriorate, but slowly.
Over last year, I fell a couple of times and permanently damaged my shoulder.
Best wishes to all
Ron
__________________
Born in 1953, 1st symptoms and misdiagnosed as essential tremor in 1992. Dx with PD in 2000.
Currently (2011) taking 200/50 Sinemet CR 8 times a day + 10/100 Sinemet 3 times a day. Functional 90% of waking day but fragile. Failure at exercise but still trying. Constantly experimenting. Beta blocker and ACE inhibitor at present. Currently (01/2013) taking ldopa/carbadopa 200/50 CR six times a day + 10/100 form 3 times daily. Functional 90% of day. Update 04/2013: L/C 200/50 8x; Beta Blocker; ACE Inhib; Ginger; Turmeric; Creatine; Magnesium; Potassium. Doing well.
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Old 08-03-2008, 03:39 PM #5
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Default regime sharing

That is so great, and you, Rick, sound as if you are holding up pretty well yourself, so something you all are doing is working. We can see what all Rick takes from his posts (see the bottom list), but would Ron please be willing to share what all he takes? Everyone is different, yes, and nothing is to be construed as medical advice, yes, etc., etc., but it would really help so everyone can compare.

I find it interesting that Ron takes dextromorphan, yet Rick does not (did I get this right?) But both seem to be holding up very well. Thoughts about this?
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Old 08-03-2008, 04:29 PM #6
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Default clarification

My signature line is a little misleading. It is not that I am always taking all those, though at times I am. But when I am actively testing something new I often put some or all of the others aside temporarily. For example, right now I am testing mucuna and also taking Acetyl-L-carnitine and alpha lipoic acid and a multi and ginseng. But all the ones I list I have evaluated and tested and consider them to be a part of my regimen. Between tests I try to take them all but one grows sick of pills. I find that I do best if I have my list to keep track of what is proven to me and take as many as I can without stressing about it.

As to the dex, it is on my someday list but I am what they call a "slow metabolizer" for it (a little goes a long way) and I just don't want to add to my liver's burden.
__________________
Born in 1953, 1st symptoms and misdiagnosed as essential tremor in 1992. Dx with PD in 2000.
Currently (2011) taking 200/50 Sinemet CR 8 times a day + 10/100 Sinemet 3 times a day. Functional 90% of waking day but fragile. Failure at exercise but still trying. Constantly experimenting. Beta blocker and ACE inhibitor at present. Currently (01/2013) taking ldopa/carbadopa 200/50 CR six times a day + 10/100 form 3 times daily. Functional 90% of day. Update 04/2013: L/C 200/50 8x; Beta Blocker; ACE Inhib; Ginger; Turmeric; Creatine; Magnesium; Potassium. Doing well.
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Old 08-04-2008, 12:56 AM #7
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Default Supplements

Quote, "would Ron please be willing to share what all he takes?"
Yes of course, I take the following
Curcumin one to two 500mg
citicoline 250mg
acetyl L carnitine 750mg
alpha lipoic acid 300mg
Since infections can have such a devastating effect, I also take a garlic capsule 1000mg and a spoon of Manuka honey.

Rick, thanks for your kind words.
Ron
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Old 08-04-2008, 07:27 AM #8
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Default regime thanks

Many, many thanks for sharing, so glad you are doing so well at 16 years!.
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Old 08-04-2008, 09:30 AM #9
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Lightbulb dear Lurch,

Quote:
Originally Posted by lurkingforacure View Post
Many, many thanks for sharing, so glad you are doing so well at 16 years!.
I have been dxd officially for 15 yrs. but in the early 1990's it was rare to get the PD diagnosis - neurologist's etc, only thought PD happened to seniority
citizens?
I was 30 -way back then...
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.


.
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.
, on Flickr
pd documentary - part 2 and 3

.


.


Resolve to be tender with the young, compassionate with the aged, sympathetic with the striving, and tolerant with the weak and the wrong. Sometime in your life you will have been all of these.
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Old 08-04-2008, 10:49 AM #10
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Default go, go, go!

I didn't know that, that is also a long time (our neuro told us 8-12 years, wheelchair around the 5th year, and then a slow decline, his exact words were "it's usually the pnuemonia that'll get ya", so comforting, those doctors), so it's great to hear that so many are doing so well so far out. And the thing I have noticed about all of that group, including yourself, pretty much without exception: all of you are doing alternative things, none have stuck strictly with the traditional Rx drugs. Those that have....sadly, I do not see that they are still around. Unless I am missing something? That speaks volumes to me.
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