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08-19-2008, 02:44 AM | #1 | |||
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. later......DB |
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08-19-2008, 07:13 AM | #2 | |||
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I read this - couldn't find a lot more info on it tho....
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Jean B This isn't the life I wished for, but it is the life I have. So I'm doing my best. |
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08-19-2008, 09:40 AM | #3 | |||
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http://en.wikipedia.org/wiki/Methylene_blue
"...Methylene blue is a monoamine oxidase inhibitor,[4] and if infused intravenously at doses exceeding 5 mg/kg, may precipitate serious serotonin toxicity, serotonin syndrome, if combined with any selective serotonin reuptake inhibitors (SSRIs) or other serotonin reuptake inhibitor (e.g., duloxetine, sibutramine, venlafaxine, clomipramine, imipramine).[5] TauRx Therapeutics has reported that methylene blue (methylthioninium chloride), under the tradename rember, may provide a way of halting or slowing the progression of Alzheimer's dementia.[6] However, the formulation used was different from that commonly available as a medicine and caution has been expressed about use of methylene blue as a treatment for Alzheimer's.[7] TauRx Therapeutics has suggested that the mechanism by which methylene blue might delay or reverse neurodegeneration in Alzheimer's disease is as an inhibitor of Tau protein aggregation. While methylene blue arguably has an effect on Tau aggregation, it also has an effect on mitochondrial function which is likely to play an important role. In vitro studies suggest that methylene blue might be an effective remedy for both Alzheimer's and Parkinson's disease by enhancing key mitochondrial biochemical pathways. It can disinhibit and increase complex IV, whose inhibition correlates with Alzheimer's disease. Methylene blue might also delay senescence as one study has shown that it extended the lifespan of IMR90 fibroblasts by more than 20 population doublings..."
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In the last analysis, we see only what we are ready to see, what we have been taught to see. We eliminate and ignore everything that is not a part of our prejudices. ~ Jean-Martin Charcot The future is already here — it's just not very evenly distributed. William Gibson |
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06-23-2009, 01:47 PM | #4 | |||
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In Remembrance
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Bought a bottle today at the local PetLand. Five bucks for a lifetime supply. You KNOW they are going to fast track this one.....
I'm going to wait a couple of weeks to clear up some other things, but will report back then.
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Born in 1953, 1st symptoms and misdiagnosed as essential tremor in 1992. Dx with PD in 2000. Currently (2011) taking 200/50 Sinemet CR 8 times a day + 10/100 Sinemet 3 times a day. Functional 90% of waking day but fragile. Failure at exercise but still trying. Constantly experimenting. Beta blocker and ACE inhibitor at present. Currently (01/2013) taking ldopa/carbadopa 200/50 CR six times a day + 10/100 form 3 times daily. Functional 90% of day. Update 04/2013: L/C 200/50 8x; Beta Blocker; ACE Inhib; Ginger; Turmeric; Creatine; Magnesium; Potassium. Doing well. |
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06-23-2009, 04:08 PM | #5 | ||
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I read somewhere that this causes green urine and blue where the whites of our eyes are, and think it is the same thing....used in the military years ago until they discovered these unsavory side effects. Anyone know, I guess Rick will report whether his wife freaked out when he opens his eyes in the morning!!!
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06-23-2009, 04:44 PM | #6 | |||
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In Remembrance
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As best I can tell the doses are too low for the "Dune" look and the blue pee thing is no problem. In fact, the doses are so low that it is like the LDN. Also, if anyone else is considering this, I have run across some discussion that indicates that where the popular press was talking about milligrams that the actual work was in micrograms. A bit of a difference. See http://groups.google.ms/group/sci.li...178fcaaf4eed25
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Born in 1953, 1st symptoms and misdiagnosed as essential tremor in 1992. Dx with PD in 2000. Currently (2011) taking 200/50 Sinemet CR 8 times a day + 10/100 Sinemet 3 times a day. Functional 90% of waking day but fragile. Failure at exercise but still trying. Constantly experimenting. Beta blocker and ACE inhibitor at present. Currently (01/2013) taking ldopa/carbadopa 200/50 CR six times a day + 10/100 form 3 times daily. Functional 90% of day. Update 04/2013: L/C 200/50 8x; Beta Blocker; ACE Inhib; Ginger; Turmeric; Creatine; Magnesium; Potassium. Doing well. |
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"Thanks for this!" says: | RLSmi (06-25-2009) |
06-26-2009, 07:11 PM | #7 | ||
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Junior Member
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Methylene Blue inactivates herpes viruses.
Alzheimer's plaques contain HSV1 particles. 95% of Parkinson's patients show HSV1 immune response. The herpes connection to PD has been known for almost a century and yet nobody has ever done a clinical trial of Acyclovir on PD. Fast track indeed... |
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