FAQ/Help |
Calendar |
Search |
Today's Posts |
|
10-12-2008, 08:32 PM | #1 | |||
|
||||
Senior Member
|
Neurosci Lett. 2008 Sep 30. [Epub ahead of print] Links
The coenzyme Q(10) status of the brain regions of Parkinson's disease patients.Hargreaves IP, Lane A, Sleiman PM. Department of Molecular Neuroscience, Institute of Neurology, Queen Square, London WC1N 3BG, UK. There is increasing evidence that impairment of mitochondrial function and oxidative damage are contributing factors to the pathophysiology of Parkinson's disease (PD). Studies have reported decreased levels of the mitochondrial electron transport chain carrier, coenzyme Q(10) (CoQ(10)) in plasma and platelets from PD patients. Although a deficit in peripheral CoQ(10) has been reported no studies have assessed the CoQ(10) status of the PD brain. In this study we investigated the CoQ(10) status of the substantia nigra, cerebellum, cortex and striatum brain regions of both PD patients and age-matched controls. The results of this study indicate a significant reduction (p=0.007) in CoQ(10) concentration in the cortex region of the brain. In conclusion, the results of this study indicate evidence of a deficit in brain CoQ(10) status may be involved in the pathophysiology of PD. PMID: 18840506 [PubMed - as supplied by publisher]
__________________
In the last analysis, we see only what we are ready to see, what we have been taught to see. We eliminate and ignore everything that is not a part of our prejudices. ~ Jean-Martin Charcot The future is already here — it's just not very evenly distributed. William Gibson |
|||
Reply With Quote |
"Thanks for this!" says: | mrsD (10-13-2008), Shake 'Em Up (10-13-2008) |
10-13-2008, 04:52 AM | #2 | |||
|
||||
Senior Member
|
FYI: all statin drugs (anti cholesterol--Lipitor, zocor, crestor, pravachol) interfere with the production of coenzyme Q10. coQ10 plasma, platlet and muscle tissue levels are decreased in patients who take statins, all patients, whether or not they have any conditions other than high cholesterol.
__________________
In the last analysis, we see only what we are ready to see, what we have been taught to see. We eliminate and ignore everything that is not a part of our prejudices. ~ Jean-Martin Charcot The future is already here — it's just not very evenly distributed. William Gibson |
|||
Reply With Quote |
10-14-2008, 11:04 AM | #3 | ||
|
|||
Member
|
Quote:
John |
||
Reply With Quote |
Reply |
|
|
Similar Threads | ||||
Thread | Forum | |||
Chiari malformation and attention deficit disorder | New Member Introductions | |||
Dystonic Tremor without Dopamine Deficit | Parkinson's Disease |